... as Paraxis/Lbx1 -positive lateral rectus EOM (yellow). Simultaneously these signals prevent the expression of the MAM marker En2 . The correct specification of the lateral rectus then facilitates the innervation by the abducens nerve. Within the branchial arches, however,the presence of Fgf8 (blue) ensures...

...Benjamin L. Martin; Richard M. Harland We have examined lbx1 expression in early X. laevis tadpoles. In contrast to amniotes, lbx1 is expressed in all of the myoblasts that contribute to the body wall musculature, as well as in a group of cells that migrate into the head. Despite this different...

... ; kpatel@rvc.ac.uk ) 26 10 2004 ©2005. 2005 Striated sphincter muscles Cloaca Perineum Chick/quail chimera Somite Segmental origin limbless MyoD Pax3 Pax7 Met Lbx1 Meox2 We thank three anonymous reviewers for comments that significantly improved...

... and differentiation of graft-derived cells were assayed using QCPN and QH1 antibodies to identify all quail cells and quail endothelial cells, respectively. Chimeric embryos were assayed for expression of myf5, myod, paraxis and lbx1 , and the synthesis of myosin heavy chain (MyHC), between 1 and 6 days later (stages...

...Roy C. Mootoosamy; Susanne Dietrich Most head muscles arise from the pre-otic axial and paraxial head mesoderm. This tissue does not form somites, yet expresses the somitic markers Lbx1 , Pax7 and Paraxis in a regionalised fashion. The domain set aside by these markers provides the lateral rectus...

... skeletal muscle. Previous studies have shown that Pax3, together with the c-Met receptor tyrosine kinase and its ligand Scatter Factor (SF) are necessary for the migration of hypaxial muscle precursors in mice. Lbx1 and Pax3 are co-expressed in all migrating hypaxial muscle precursors, raising...

...Henning Brohmann; Krzysztof Jagla; Carmen Birchmeier ABSTRACT The homeobox gene Lbx1 is expressed in migrating hypaxial muscle precursor cells during development. These precursors delaminate from the lateral edge of the dermomyotome and form distinct streams that migrate over large distances, using...

.... Migratory precursors are also correctly specified, as monitored by the expression of Lbx1 . However, these cells remain aggregated and fail to take up long range migration. We conclude that parallel but independent cues converge on the migratory hypaxial precursors in the dermomyotomal lip after...

... of this musculature, we cloned the chick Lbx1 gene that is specific to prospective hypaxial myoblasts at occipital, cervical and limb levels. Using this gene as a marker, we characterised the anatomical structures that produce the signals necessary for the specification of the hypaxial musculature by ablating them...