...Alexander C. Cerny; Gregor Bucher; Reinhard Schröder; Martin Klingler During Drosophila segmentation, gap genes function as short-range gradients that determine the boundaries of pair-rule stripes. A classical example is Drosophila Krüppel ( Dm'Kr ) which is expressed in the middle...

... is required for activation of the gap genes hunchback and Krüppel . Given the large RNAi deletion phenotype and its regulation of hunchback and Krüppel, even-skipped seems to act as an über-gap gene in Oncopeltus , indicating that it may have both upstream and downstream roles in segmentation...

... expression ( Rivera-Pomar et al., 1995 ). Second, the posterior Tc'giant domain appears right within the Krüppel domain, and co-expression of both genes is observed in segment T3 for an extended time period. This again is in contrast to Drosophila , where strong mutual repression with Krüppel...