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Keywords: Knockout
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Journal Articles
Journal: Development
Development (2020) 147 (4): dev187385.
Published: 26 February 2020
... in any medium provided that the original work is properly attributed. Summary: Genome-edited larp6a and larp6b double-knockout zebrafish appear morphologically and behaviourally wild type and are fertile. Larp6 proteins are, however, required maternally for normal oocyte development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4233–4243.
Published: 1 November 2006
..., leading to biliary cell differentiation. This study was undertaken to analyze how inactivation of the Cebpa gene affects biliary cell differentiation and gene expression of the regulatory genes for that differentiation, including Hnf1b and Hnf6 . In the knockout mouse liver at midgestation stages...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (22): 5055–5068.
Published: 15 November 2005
..., USA † These authors contributed equally to this work ‡ Present address: Hôpital Bichat–Claude-Bernard, 46 Rue Henri-Huchard, 75018 Paris, France 14 9 2005 ©2005. 2005 Homologous recombination Knockout Hypertrophic cartilage Chondrocyte Hereditary multiple...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (15): 3431–3443.
Published: 1 August 2005
... equally to this work 23 5 2005 ©2005. 2005 Foxa1 Knockout Prostate Foxa2 Shh Androgen Mouse Gene inactivation studies in the mouse, combined with organ culture and tissue recombination, have highlighted the essential roles of androgenic signaling and epithelial-stromal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (23): 5883–5895.
Published: 1 December 2004
... environment for blood vessels to invade. * Authors for correspondence (e-mail: domi@itsa.ucsf.edu ; zena@itsa.ucsf.edu ) 25 9 2004 © 2004. 2004 Collagenase MMP Homologous recombination Knockout Hypertrophic cartilage Chondrocyte Trabecular bone Collagen Aggrecan Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (7): 1619–1628.
Published: 1 April 2004
... basement membrane protein knockouts, these data suggest that laminin is sufficient for basement membrane-like matrices during early development, but at later stages the specific composition of components including collagen IV defines integrity, stability and functionality. In contrast to invertebrates...
Journal Articles
Journal: Development
Development (2004) 131 (4): 903–913.
Published: 15 February 2004
.... To delineate the effects of Math1 on CGC differentiation, we generated and studied primary cultures of CGC progenitors from Math1 / lacZ knockout mice. Rhombic lip precursors appeared properly positioned, expressed CGC-specific markers, and maintained Math1 promoter activity in vivo and in vitro,suggesting...
Journal Articles
Journal: Development
Development (2003) 130 (2): 401–410.
Published: 15 January 2003
... GnRH neurons Peripheral nerve Peripheral neuropathy Dysmyelination Homologous recombination Knockout Targeted inactivation Gene targeting COE2 O/E3 Olf/Ebf genes ( Garel et al.,1997 ; Hagman et al.,1993 ; Malgaretti et al.,1997 ; Wang and Reed,1993 ; Wang et al.,1997 ) (reviewed...
Journal Articles
Journal: Development
Development (2002) 129 (2): 527–538.
Published: 15 January 2002
... genetic data show that loss of Msx1 function does not rescue Splotch mutants to viability. Although we have not examined the hearts of Msx1-Pax3 double mutant embryos, the simplest explanation for this lack of rescue is that the Msx1 knockout fails to suppress the lethal cardiac defect of Splotch...
Journal Articles
Journal: Development
Development (2001) 128 (11): 2095–2106.
Published: 1 June 2001
... mesenchyme development. Table 1. Table 2. *Author for correspondence (e-mail: dornitz@pcg.wustl.edu ) 14 3 2001 © 2001. 2001 FGF9 FGF FGF receptor Lung Mesenchyme Mouse Knockout Chicken lung graft experiments dating back to 1933 demonstrated...