.... Together, our data suggest that JNK signalling is required to establish stem cell-dependent Wnt expression after posterior injury. Given that Jun is known to be required in vertebrates for the expression of Wnt and Wnt target genes, we propose that this interaction may be conserved and is an instructive...

... the molecular pathways active during epidermal barrier formation. Akt signaling increased as the barrier wave crossed epidermis and Jun was transiently dephosphorylated. Inhibitor experiments on embryonic explants showed that the dephosphorylation of Jun was dependent on both Akt and protein phosphatase 2A(Pp2a...

... defects and fail to express π markers. We show that FOS-1 is expressed at π cell specification and can bind in vitro to egl-13 upstream regulatory sequence (URS) as a heterodimer with C. elegans Jun. * Author for correspondence (e-mail: apnewman@uh.edu ) 22 8 2007 © 2007. 2007 LIN...

...Axel Behrens; Jody Haigh; Fatima Mechta-Grigoriou; Andras Nagy; Moshe Yaniv; Erwin F. Wagner Jun is a major component of the heterodimeric transcription factor AP-1 and is essential for embryonic development, as foetuses that lack Jun die at mid-gestation. Ubiquitous mosaic inactivation...

...Ursula Weber; Nuria Paricio; Marek Mlodzik ABSTRACT Jun acts as a signal-regulated transcription factor in many cellular decisions, ranging from stress response to proliferation control and cell fate induction. Genetic interaction studies have suggested that Jun and JNK signaling are involved...