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Keywords: Jagged 1
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Journal Articles
Journal: Development
Development (2010) 137 (21): 3569–3579.
Published: 1 November 2010
... resulted in upregulation of jagged 1 in both epidermis and dermis. When Notch was activated in the absence of epidermal jagged 1, jagged 1 was not upregulated in the dermis, and epidermal thickening, blister formation, accumulation of T cells and stromal cells were inhibited. Gene expression profiling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (13): 2251–2261.
Published: 1 July 2008
...-Catenin Notch1 Jagged 1 Inner ear Inner ear development is an excellent example of how a Darwinian `organ of extreme perfection and complication' can arise from simple origins. The inner ear derives from a patch of thickened ectoderm, the otic placode, lying next to the posterior hindbrain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4427–4438.
Published: 15 November 2006
..., where commitment to hair lineages occurs. Deletion of jagged 1 ( Jag1 ) results in inhibition of the hair growth cycle and conversion of hair follicles into cysts of cells undergoing interfollicular epidermal differentiation. Conversely, activation of Notch in adult epidermis triggers expansion...