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Keywords: JNK signaling
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Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (3): dev199449.
Published: 3 February 2022
... signaling after amputation. Pharmacological inhibition of JNK signaling caused failure to induce hyperproliferation and resulted in regenerative defects. Such defects were abrogated by simultaneous knockdown of plac8-A expression. Thus, JNK-dependent suppression of plac8-A expression is indispensable...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (19): dev191155.
Published: 9 October 2020
... dendrite pruning. Raw negatively regulates JNK signaling during development ( Byars et al., 1999 ; Bates et al., 2008 ). To test a possible role of raw in regulating JNK signaling in ddaC neurons, we made use of the JNK reporter puc-lacZ to examine the expression of the target gene puckered...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (20): 3500–3511.
Published: 15 October 2015
... checkpoint that allows regeneration to occur. This defect is likely to be caused by abnormally high expression of puckered , a negative regulator of Jun N-terminal kinase (JNK) signaling, at the wound site. Insufficient JNK signaling leads to insufficient expression of an insulin-like peptide, dILP8, which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4771–4781.
Published: 1 December 2006
... components. Blocking Jun-N-terminal kinase (JNK) signaling, which can induce caspase-independent cell death, significantly rescued ventral eye loss in L or Ser mutants. However, blocking both caspase-dependent cell death and JNK signaling together showed stronger rescues of the L - or Ser- mutant eye...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (10): 1845–1856.
Published: 15 May 2001
... ( puc ) gene is required to fine-tune follicle cell rearrangements that create the structures of the anterior eggshell. puc encodes a dual specificity phosphatase that down-regulates Jun kinase (JNK) signaling during epithelial morphogenesis (Martín- Blanco et al., 1998; Ring and Martinez-Arias, 1993...
Journal Articles
Journal: Development
Development (2000) 127 (16): 3619–3629.
Published: 15 August 2000
...Ursula Weber; Nuria Paricio; Marek Mlodzik ABSTRACT Jun acts as a signal-regulated transcription factor in many cellular decisions, ranging from stress response to proliferation control and cell fate induction. Genetic interaction studies have suggested that Jun and JNK signaling are involved...