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Keywords: Intestinal stem cells
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Journal Articles
Journal: Development
Development (2021) 148 (10): dev191924.
Published: 27 May 2021
... major lipid metabolic pathways: the build-up of lipids, called de novo lipogenesis, and the breakdown of lipids, called fatty acid beta-oxidation. We cover the recent literature on hematopoietic stem cells, intestinal stem cells, neural stem/progenitor cells and cancer stem cells, where these two lipid...
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (2): dev167643.
Published: 29 January 2019
... Niche Germline stem cells Somatic stem cells Testis Intestine Intestinal stem cells Enterocytes Wing disc Cytokines Proliferation Survival Differentiation Cell competition Niche competition Inflammation Regeneration Cellular plasticity Cell reprogramming In the early 1990s...
Journal Articles
Journal: Development
Development (2017) 144 (7): 1177–1186.
Published: 1 April 2017
... symmetric signalling states. We apply this model to the adult intestinal stem cell (ISC) of Drosophila , the fate of which is stochastic but dependent on the Notch/Delta pathway. We observe a correlation between signalling state in cell pairs and their contact area. We interpret this behaviour in terms...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (10): 2014–2023.
Published: 15 May 2014
... dispatched between the two daughters upon stem cell mitosis. In the adult Drosophila midgut, the intestinal stem cell (ISC) divides to generate a new ISC and an enteroblast (EB) differentiating daughter. Notch signalling activity restricted to the EB regulates intestinal cell fate decision. Here, we show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (17): 3532–3540.
Published: 1 September 2013
.... In a screen for genes that regulate cell lineage determination in the posterior midgut, we identified that the Osa-containing SWI/SNF (Brahma) chromatin-remodeling complex regulates Drosophila midgut homeostasis. Mutations in subunits of the Osa-containing complex result in intestinal stem cell (ISC...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (21): 3917–3925.
Published: 1 November 2012
...Xiankun Zeng; Steven X. Hou Like the mammalian intestine, the Drosophila adult midgut is constantly replenished by multipotent intestinal stem cells (ISCs). Although it is well known that adult ISCs arise from adult midgut progenitors (AMPs), relatively little is known about the mechanisms...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (6): 1045–1055.
Published: 15 March 2011
...Benoît Biteau; Heinrich Jasper Precise control of somatic stem cell proliferation is crucial to ensure maintenance of tissue homeostasis in high-turnover tissues. In Drosophila , intestinal stem cells (ISCs) are essential for homeostatic turnover of the intestinal epithelium and ensure epithelial...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (13): 2255–2264.
Published: 1 July 2009
... by a population of multipotent intestinal stem cells (ISCs) that resides in epithelial niches. Adenomatous polyposis coli ( Apc ), a tumor suppressor gene conserved in both invertebrates and vertebrates, is known to play a role in multiple developmental processes in Drosophila . Here, we examine the consequences...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2000) 127 (12): 2763–2772.
Published: 15 June 2000
... Intestinal stem cells All metazoan embryos develop an inner gut cavity for the general purpose of nutrient absorption and gas exchange. The gut is lined by an endodermal epithelium and surrounded by mesenchymal cells in triploblastic animals, and has achieved a sophisticated level of patterning...