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Keywords: Induction
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Journal Articles
Journal: Development
Development (2021) 148 (10): dev180794.
Published: 17 May 2021
... Summary: This Review discusses how understanding the relationship between electrical signaling and developmental systems requires the definition of hierarchical levels of action provided by bioelectric signaling. Bioelectric signaling Development Competence Induction Morphogenetic fields...
Journal Articles
Journal: Development
Development (2018) 145 (2): dev155663.
Published: 22 January 2018
...Tara M. Fresques; Gary M. Wessel ABSTRACT Specification of the germ cell lineage is required for sexual reproduction in animals. The mechanism of germ cell specification varies among animals but roughly clusters into either inherited or inductive mechanisms. The inductive mechanism, the use of cell...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (8): 1382–1398.
Published: 15 April 2017
... sexual dimorphism, bud induction, branching morphogenesis and cellular differentiation. * Author for correspondence ( mshen@columbia.edu ) Competing interests The authors declare no competing or financial interests. © 2017. Published by The Company of Biologists Ltd 2017 Summary...
Journal Articles
Journal: Development
Development (2009) 136 (3): 461–472.
Published: 1 February 2009
... 2009. 2009 RDH10 Retinol dehydrogenase Short chain dehydrogenase/reductase Retinoic acid Morphogen Gradient Spemann's organizer Gastrulation Induction Pattern formation Hindbrain CNS Xenopus Regional specification is a fundamental process during early development of the central...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (24): 4165–4177.
Published: 15 December 2008
... commitment just prior to morphological differentiation. * Author for correspondence (e-mail: mbronner@caltech.edu ) 17 10 2008 © 2008. 2008 Olfactory placode Nasal placode Chick Competence Specification Commitment Induction Ectoderm Cranial sensory placodes arise...
Journal Articles
Journal: Development
Development (2008) 135 (23): 3903–3910.
Published: 1 December 2008
...Chang-Soo Hong; Byung-Yong Park; Jean-Pierre Saint-Jeannet Two independent signals are necessary for neural crest (NC) induction in Xenopus : a Bmp signal, which must be partially attenuated by Bmp antagonists, and a separate signal mediated by either a canonical Wnt or an Fgf. The mesoderm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (10): 1863–1874.
Published: 15 May 2008
... interactions between the neural tube and adjacent ectoderm. This induction triggers expression of Pax3, ingression of placode cells and their differentiation into neurons. However, the molecular nature of the underlying signals remains unknown. Here, we investigate the role of PDGF signaling in ophthalmic...
Journal Articles
Journal: Development
Development (2008) 135 (2): 249–258.
Published: 15 January 2008
... FoxE3 expression posteriorly. These data provide the first direct evidence of the involvement of Notch signaling in lens induction. The obligate integration of inputs of a field-selector (Otx2)and localized signaling (Notch) within target cis-regulatory elements might be a general mechanism of organ...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (24): 4933–4944.
Published: 15 December 2006
... Wnt FGF Erk Signaling Lens Induction Mouse Multiple signaling pathways are involved in early-lens morphogenesis,including bone morphogenic proteins (BMPs), fibroblast growth factors (FGFs),Wnts and hedgehog (Hh). Genetic inactivation of Bmp4 or Bmp7 in mice abolished Sox2 expression...
Journal Articles
Journal: Development
Development (2006) 133 (19): 3817–3826.
Published: 1 October 2006
... and Sox10 expression domains. Although morpholino-mediated knockdown of Sox8 protein did not prevent the formation of neural crest progenitors, the timing of their induction was severely affected. This delay in neural crest specification had dramatic consequences on the development of multiple lineages...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (14): 2705–2717.
Published: 15 July 2006
... colliculus, or optic tectum, is that axons carrying similar amounts of Eph receptor terminate near to one another on the target structure. I show how the previously proposed marker induction model embodies this principle and predicts these results. I then describe a new version of the model in which...
Journal Articles
Journal: Development
Development (2006) 133 (5): 877–887.
Published: 1 March 2006
... signaling. This suggests a two-step model of craniofacial placode induction in which ectoderm first acquires pre-placodal region identity, and subsequently differentiates into particular craniofacial placodes under the influence of local inducing signals. We thank Xiomara Padilla and Juemei Wang...
Journal Articles
Journal: Development
Development (2005) 132 (9): 2115–2124.
Published: 1 May 2005
...@nidcd.nih.gov ) 18 2 2005 ©2005. 2005 References Baker, C. V. and Bronner-Fraser, M. ( 2001 ). Vertebrate cranial placodes I. Embryonic induction. Dev. Biol. 232 , 1 -61. Bell, E., Wingate, R. J. and Lumsden, A. ( 1999 ). Homeotic transformation of rhombomere identity after...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 1967–1978.
Published: 1 May 2004
... are essential for mesodermal induction, and that these factors are expressed in ABa, but not ABp, descendants. We provide evidence that the first Notch interaction functions largely, if not entirely, to prevent TBX-37, TBX-38 expression in ABp descendants. Neither the second Notch interaction nor TBX-37, TBX-38...
Journal Articles
Journal: Development
Development (2003) 130 (21): 5179–5190.
Published: 1 November 2003
... identified as a localized muscle determinant, is also required for mesenchyme induction, and that it plays a role in making the cell response differ between notochord and mesenchyme induction. A zygotic event involving snail expression downstream of maternal macho-1 mediates the suppression of notochord...
Journal Articles
Journal: Development
Development (2003) 130 (21): 5091–5101.
Published: 1 November 2003
...Susan C. Chapman; Frank R. Schubert; Gary C. Schoenwolf; Andrew Lumsden Previous studies of head induction in the chick have failed to demonstrate a clear role for the hypoblast and anterior definitive endoderm (ADE) in patterning the overlying ectoderm, whereas data from both mouse and rabbit...
Journal Articles
Journal: Development
Development (2003) 130 (15): 3379–3390.
Published: 1 August 2003
... arising from the underlying mesoderm and adjacent neurectoderm. In mice, Fgf3 is expressed in the neurectoderm prior to and concomitant with placode induction and otic vesicle formation,but its absence affects only the later stages of otic vesicle morphogenesis. We show here that mouse Fgf10 is expressed...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2027–2037.
Published: 15 May 2003
... of these may act as composite mechanisms in two different ways. The simple categories are cell autonomous mechanisms in which cells enter into specific arrangements (`patterns') without interacting, inductive mechanisms in which cell communication leads to changes in pattern by reciprocal or hierarchical...
Journal Articles
Journal: Development
Development (2002) 129 (24): 5731–5741.
Published: 15 December 2002
....,1993 ). In summary, we provide a genomic analysis of the consequences of neural crest induction, creating a molecular profile of a cell type that cannot be purified or identified. Importantly, this analysis suggests previously unrecognized similarities with other migratory cells such as endothelial...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3633–3644.
Published: 1 August 2002
... by examining chicken somite segmentation as a model system. By transplanting a small group of cells taken from a presumptive border into a non-segmentation site, we have found a novel inductive event where posteriorly juxtaposed cells to the next-forming border instruct the anterior cells to become separated...