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Keywords: IL7R
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev200139.
Published: 24 January 2022
... hematopoietic stem cells (HSCs), many TLCs are of fetal origin and poorly generated from adult HSCs. Here, we sought to further understand murine TLC development and the roles of Flk2 and IL7Rα, two cytokine receptors with known function in traditional lymphopoiesis. Using Flk2- and Il7r-Cre lineage tracing, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (14): dev176180.
Published: 22 July 2019
... lineage tracing of cells with an expression history of IL7Rα, a marker exclusively associated with the lymphoid lineage in adult hematopoiesis. Surprisingly, we found that Il7r-Cre labeled fetal-derived, adult trMacs. Labeling was almost complete in some tissues and partial in others. The putative...
Includes: Supplementary data