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Keywords: ICM
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Journal Articles
Journal: Development
Development (2013) 140 (21): 4311–4322.
Published: 1 November 2013
...Néstor Saiz; Joanna B. Grabarek; Nitin Sabherwal; Nancy Papalopulu; Berenika Plusa During mouse pre-implantation development, extra-embryonic primitive endoderm (PrE) and pluripotent epiblast precursors are specified in the inner cell mass (ICM) of the early blastocyst in a ‘salt and pepper’ manner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (1): 129–139.
Published: 1 January 2012
... endoderm (PrE). A subset of cells within the inner cell mass (ICM) of the blastocyst does not respond to differentiation signals and forms the pluripotent epiblast, which gives rise to all of the tissues in the adult body. How this group of cells is set aside remains unknown. Recent studies documented...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 715–724.
Published: 1 March 2010
...Yojiro Yamanaka; Fredrik Lanner; Janet Rossant Primitive endoderm (PE) and epiblast (EPI) are two lineages derived from the inner cell mass (ICM) of the E3.5 blastocyst. Recent studies showed that EPI and PE progenitors expressing the lineage-specific transcriptional factors Nanog and Gata6...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (18): 3081–3091.
Published: 15 September 2008
... in deeper layers of the ICM ( Fig. 5C ), those cells usually exhibited lower levels of fluorescence than did GFP-positive/Gata4-positive cells in the PrE layer (see Fig. S4 in the supplementary material ). In 80.2% ( n =96) of embryos of >100 cells, Gata4-positive cells were restricted to the PrE...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (1985) 86 (1): 311–336.
Published: 1 April 1985
..., as a population, are a little ahead of inside cells in their cell cycling. Additionally we present evidence that, within at least some individual inner cell masses (ICM), there is intraembryo variation in the time at which inside cell developmental potential becomes restricted. /. Embryol. exp Morph. 86, 311-336...