... irregular ICs were observed ( Fig. 4B ), further suggesting that actin filament formation and organization and caspase activation are sensitive to the levels of Nutcracker. In Drosophila , two IAPs have been shown to directly inhibit active caspases: DIAP1 and DIAP2 (Thread and Inhibitor...

... Drosophila eye Caspase Drice Dronc Notch EGF receptor Hid IAP Apoptosis During development, programmed cell death is regulated by cell-cell signals that either promote or inhibit caspase activation ( Meier et al., 2000a ). The biochemical mechanisms of extracellular regulation...