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Keywords: Hypertrophy
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Journal Articles
Journal: Development
Development (2022) 149 (11): dev196220.
Published: 6 June 2022
... cartilage that expressed chondrocyte hypertrophy markers and readily underwent mineralization after ectopic transplantation. In contrast, the slowly growing GDF5 + cells derived from SOX9 + cells formed cartilage that tended to express low to undetectable levels of chondrocyte hypertrophy markers...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev167197.
Published: 25 October 2018
...-contracting EDL and slow-contracting SOL muscles, particularly between 4 and 6 weeks ( Fig. 1 , Fig. S1 ). Additionally, we found myofibers to transition in size throughout development, with the establishment of a heterogeneous adult-like population at 6 weeks of age. The hypertrophy we observed between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2898–2906.
Published: 15 August 2016
..., but it was recently suggested that such recruitment is not obligatory: overload hypertrophy after synergist ablation of the plantaris muscle appeared normal in transgenic mice in which most of the satellite cells were abolished. When we essentially repeated these experiments analyzing the muscles...
Journal Articles
Journal: Development
Development (2016) 143 (16): 3012–3023.
Published: 15 August 2016
... that AP-1 promotes chondrocyte hypertrophy. Sox9 and Jun co-bound and co-activated a Col10a1 enhancer in Sox9 and AP-1 motif-dependent manners consistent with their combined action promoting hypertrophic gene expression. Together, the data support a model in which AP-1 family members contribute to Sox9...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2135–2146.
Published: 15 June 2016
... within a 60-kb domain centered around Nppb . Both promoters and several potential regulatory elements interact with each other in a similar manner in different tissues and developmental stages. The distribution of H3K27ac and the association of Pol2 across the locus changed during cardiac hypertrophy...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (17): 3657–3668.
Published: 1 September 2013
... and layer-specific block of cell cycle progression. The number of cells generated by this glial progenitor and hence the control of perineurial hyperplasia correlate with the length of the abdominal nerves. By contrast, the wrapping and subperineurial glia layers show enormous hypertrophy in response...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 495–505.
Published: 1 February 2009
... and the manifestation of a subset of muscular-based disease have previously been attributed to mutations in key structural proteins. Our study reveals an essential requirement for direct transcriptional regulation of sarcomere integrity, in the context of enabling foetal cardiomyocyte hypertrophy, maintenance...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (19): 4729–4739.
Published: 1 October 2003
... the osteogenic influence of Ihh on the periosteum, but does not interfere with the cell cycle-promoting component of Hh signalling. * Author for correspondence (e-mail: archer@cardiff.ac.uk ) 15 5 2003 © 2003. 2003 Cbfa-1 Ihh Sox9 Hypertrophy Chondrocyte Membrane bone...