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Keywords: Human embryonic stem cell
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Journal Articles
In collection:
Stem cells & regeneration
Ludovic Zimmerlin, Tea Soon Park, Jeffrey S. Huo, Karan Verma, Sarshan R. Pather, C. Conover Talbot, Jr., Jasmin Agarwal, Diana Steppan, Yang W. Zhang, Michael Considine, Hong Guo, Xiufeng Zhong, Christian Gutierrez, Leslie Cope, M. Valeria Canto-Soler, Alan D. Friedman, Stephen B. Baylin, Elias T. Zambidis
Journal:
Development
Development (2016) 143 (23): 4368–4380.
Published: 1 December 2016
... of conventional human ESCs and transgene-independent iPSC lines can be reverted to stable naive states using WNT, MEK/ERK and tankyrase inhibition. Differentiation Ground state Human embryonic stem cell Induced pluripotent stem cell Naïve pluripotency Although human induced pluripotent stem...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Tamara Zdravkovic, Kristopher L. Nazor, Nicholas Larocque, Matthew Gormley, Matthew Donne, Nathan Hunkapillar, Gnanaratnam Giritharan, Harold S. Bernstein, Grace Wei, Matthias Hebrok, Xianmin Zeng, Olga Genbacev, Aras Mattis, Michael T. McMaster, Ana Krtolica, Diana Valbuena, Carlos Simón, Louise C. Laurent, Jeanne F. Loring, Susan J. Fisher
Journal:
Development
Development (2015) 142 (23): 4010–4025.
Published: 1 December 2015
.... Laurent; Jeanne F. Loring; Susan J. Fisher Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Nathan J. Palpant, Lil Pabon, Meredith Roberts, Brandon Hadland, Daniel Jones, Christina Jones, Randall T. Moon, Walter L. Ruzzo, Irwin Bernstein, Ying Zheng, Charles E. Murry
Journal:
Development
Development (2015) 142 (18): 3198–3209.
Published: 15 September 2015
.../nodal, BMPs and Wnt/β-catenin that define anterior-posterior patterning and specify downstream derivatives including cardiomyocyte, endothelial and hematopoietic cells. We used human embryonic stem cells to explore how these pathways control mesodermal fate choices in vitro. Varying doses of activin...
Includes: Supplementary data
Journal Articles
Nathan J. Palpant, Lil Pabon, Jeremy S. Rabinowitz, Brandon K. Hadland, Cristi L. Stoick-Cooper, Sharon L. Paige, Irwin D. Bernstein, Randall T. Moon, Charles E. Murry
Journal:
Development
Development (2013) 140 (18): 3799–3808.
Published: 15 September 2013
... suppression of Wnt/β-catenin signaling, but the mechanism for this is not well understood. By analyzing gene expression and chromatin dynamics during directed differentiation of human embryonic stem cells (hESCs), we identified a suppressor of Wnt/β-catenin signaling, transmembrane protein 88 (TMEM88...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2013) 140 (12): 2611–2618.
Published: 15 June 2013
...Zhong-Wei Du; Li-Xiang Ma; Christian Phillips; Su-Chun Zhang The role of miRNAs in neuroectoderm specification is largely unknown. We screened miRNA profiles that are differentially changed when human embryonic stem cells (hESCs) were differentiated to neuroectodermal precursors (NEP...
Includes: Supplementary data
