... segments. This homeotic transformation is caused by loss of abdominal Hox gene expression, likely due to expanded Tc-Krüppel expression. Our findings support the theory that the neuroblast timer series was co-opted for use in insect segment patterning, and contribute to our growing understanding...

... Hox gene Although the morphological design of organisms is determined by genetic information, morphologies can also be altered by environmental stimuli, known as phenotypic plasticity or polyphenism ( Nijhout, 2003 ). Insects are a major group of arthropods and share a basic body plan...

...Simon G. Sprecher; Rolf Urbach; Gerhard M. Technau; Filippo M. Rijli; Heinrich Reichert; Frank Hirth In Drosophila , evolutionarily conserved transcription factors are required for the specification of neural lineages along the anteroposterior and dorsoventral axes, such as Hox genes...

...-mail: francois.karch@zoo.unige.ch ) 22 5 2006 © 2006. 2006 Bithorax Hox gene Abd-B Chromatin boundary Insulator PRE PTS Drosophila The three homeotic genes of the Drosophila bithorax complex(BX-C), Ubx, abd-A and Abd-B , specify the identity of the 3rd thoracic segment (T3...

.... Whereas previous syntheses have tended to focus on the roles of genes from a single gene family, most notably Hox genes, we emphasize the importance of considering the interactions among multiple genes from different gene families for understanding the evolution of complex developmental systems. Our...

... were cut into halves and the medial side is displayed. B1 and B2, branchial arches 1 and 2; E, endoderm; M, dorsal mesocardium. The products of the 3′ Hox genes are essential for the morphogenesis of the pharynx (reviewed in Rijli et al., 1998 ). Expression of Hoxa1 and Hoxb1...

... with a temperature-sensitive type II receptor mutant, as well as heat-shock induction experiments, show that the DBL-1 pathway acts during an interval that extends from two to one cell generation before ray neurons are born and begin to differentiate. In a mutant of the AbdominalB class Hox gene egl-5 , rays...

...Stefan Jungbluth; Esther Bell; Andrew Lumsden ABSTRACT Hox genes have been implicated in specifying positional values along the anteroposterior axis of the caudal central nervous system, but their nested and overlapping expression has complicated the understanding of how they confer specific neural...

...Karin Brunschwig; Claudia Wittmann; Ralf Schnabel; Thomas R. Bürglin; Heinz Tobler; Fritz Müller The Caenorhabditis elegans lin-39, mab-5 and egl-5 Hox genes specify cell fates along the anterior-posterior body axis of the nematode during postembryonic development, but little is known about Hox...

...Miguel Manzanares,; Sabine Cordes,; Linda Ariza-McNaughton,; Virginia Sadl,; Kamala Maruthainar,; Greg Barsh; Robb Krumlauf During anteroposterior patterning of the developing hindbrain, the anterior expression of 3′ Hox genes maps to distinct rhombomeric boundaries and, in many cases...

...Craig P. Hunter; Jeanne M. Harris; Julin N. Maloof; Cynthia Kenyon In Caenorhabditis elegans males, a row of epidermal precursor cells called seam cells generates a pattern of cuticular alae in anterior body regions and neural sensilla called rays in the posterior. The Hox gene mab-5 is required...

...Julin N. Maloof; Jennifer Whangbo; Jeanne M. Harris; Gregg D. Jongeward; Cynthia Kenyon ABSTRACT The specification of body pattern along the anteroposterior (A/P) body axis is achieved largely by the actions of conserved clusters of Hox genes. Limiting expression of these genes to localized...

...Alastair Morrison; Linda Ariza-McNaughton; Alex Gould; Mark Featherstone; Robb Krumlauf ABSTRACT From an evolutionary perspective, it is important to understand the degree of conservation of cis -regulatory mechanisms between paralogous Hox genes. In this study, we have used transgenic analysis...

...Jeanne Harris; Lee Honigberg; Naomi Robinson; Cynthia Kenyon ABSTRACT In C. elegans , the Hox gene mab-5 , which specifies the fates of cells in the posterior body region, has been shown to direct the migrations of certain cells within its domain of function. mab-5 expression switches...

... by Company of Biologists 1996 quail-chick chimaera fate map hox gene rhombomere hindbrain The hindbrain undergoes a fundamental change in its organisation during development. The early embryonic hindbrain (at E2-E5) is characterised by transient segmental swellings ( Vaage, 1969...

...Stephen J. Salser; Cynthia Kenyon ABSTRACT Hox genes establish body pattern throughout the animal kingdom, but the role these genes play at the cellular level to modify and shape parts of the body remains a mystery. We find that the C. elegans Antennapedia homolog, mab-5 , sequentially programs...

... is maintained in both migrating neural crest cells and those positioned within the second branchial arch and associated ganglia. These results suggest that Hoxa3 expression is cellautonomous in r6 and its associated neural crest. Our results suggest that neural crest cells expressing the same Hox gene...

.... Here, we investigated expression of the ascidian labial group Hox gene HrHox-1 in the development of Halo-cynthia roretzi. HrHox-1 showed a spatially restricted expression pattern along the anterior-posterior axis, which is remarkably similar to that of the vertebrate gene, Hoxb-1 . The expression...

... genes may be different in these early and late roles. The combined action of many Hox genes on distinct developmental processes contribute to pattern asymmetry along the A-P axis. © 1994 by Company of Biologists 1994 Hox gene limb bud morphogenesis axis specification anteroposterior...

... (and the fins of the Crossopterygians) in terms of developmental mechanisms? © 1994 by Company of Biologists 1994 limb development palaeontogeny Hox gene tetrapod The developmental basis of macroevolution has long been ignored by the neo-Darwinian synthesis, with its emphasis...