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Keywords: Hox gene
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Journal Articles
Journal:
Development
Development (2021) 148 (16): dev199719.
Published: 20 August 2021
... segments. This homeotic transformation is caused by loss of abdominal Hox gene expression, likely due to expanded Tc-Krüppel expression. Our findings support the theory that the neuroblast timer series was co-opted for use in insect segment patterning, and contribute to our growing understanding...
Includes: Supplementary data
Journal Articles
Yasuhiro Sugime, Kohei Oguchi, Hiroki Gotoh, Yoshinobu Hayashi, Masatoshi Matsunami, Shuji Shigenobu, Shigeyuki Koshikawa, Toru Miura
Journal:
Development
Development (2019) 146 (5): dev171942.
Published: 4 March 2019
... Hox gene Although the morphological design of organisms is determined by genetic information, morphologies can also be altered by environmental stimuli, known as phenotypic plasticity or polyphenism ( Nijhout, 2003 ). Insects are a major group of arthropods and share a basic body plan...
Includes: Supplementary data
Journal Articles
Simon G. Sprecher, Rolf Urbach, Gerhard M. Technau, Filippo M. Rijli, Heinrich Reichert, Frank Hirth
Journal:
Development
Development (2006) 133 (21): 4331–4339.
Published: 1 November 2006
...Simon G. Sprecher; Rolf Urbach; Gerhard M. Technau; Filippo M. Rijli; Heinrich Reichert; Frank Hirth In Drosophila , evolutionarily conserved transcription factors are required for the specification of neural lineages along the anteroposterior and dorsoventral axes, such as Hox genes...
Journal Articles
Jozsef Mihaly, Stéphane Barges, Laszlo Sipos, Robert Maeda, Fabienne Cléard, Ilham Hogga, Welcome Bender, Henrik Gyurkovics, François Karch
Journal:
Development
Development (2006) 133 (15): 2983–2993.
Published: 1 August 2006
...-mail: francois.karch@zoo.unige.ch ) 22 5 2006 © 2006. 2006 Bithorax Hox gene Abd-B Chromatin boundary Insulator PRE PTS Drosophila The three homeotic genes of the Drosophila bithorax complex(BX-C), Ubx, abd-A and Abd-B , specify the identity of the 3rd thoracic segment (T3...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2000) 127 (24): 5233–5244.
Published: 15 December 2000
.... Whereas previous syntheses have tended to focus on the roles of genes from a single gene family, most notably Hox genes, we emphasize the importance of considering the interactions among multiple genes from different gene families for understanding the evolution of complex developmental systems. Our...
Journal Articles
Journal:
Development
Development (2000) 127 (8): 1553–1562.
Published: 15 April 2000
... were cut into halves and the medial side is displayed. B1 and B2, branchial arches 1 and 2; E, endoderm; M, dorsal mesocardium. The products of the 3′ Hox genes are essential for the morphogenesis of the pharynx (reviewed in Rijli et al., 1998 ). Expression of Hoxa1 and Hoxb1...
Journal Articles
Journal:
Development
Development (1999) 126 (24): 5819–5831.
Published: 15 December 1999
... with a temperature-sensitive type II receptor mutant, as well as heat-shock induction experiments, show that the DBL-1 pathway acts during an interval that extends from two to one cell generation before ray neurons are born and begin to differentiate. In a mutant of the AbdominalB class Hox gene egl-5 , rays...
Journal Articles
Specification of distinct motor neuron identities by the singular activities of individual Hox genes
Journal:
Development
Development (1999) 126 (12): 2751–2758.
Published: 15 June 1999
...Stefan Jungbluth; Esther Bell; Andrew Lumsden ABSTRACT Hox genes have been implicated in specifying positional values along the anteroposterior axis of the caudal central nervous system, but their nested and overlapping expression has complicated the understanding of how they confer specific neural...
Journal Articles
Journal:
Development
Development (1999) 126 (7): 1537–1546.
Published: 1 April 1999
...Karin Brunschwig; Claudia Wittmann; Ralf Schnabel; Thomas R. Bürglin; Heinz Tobler; Fritz Müller The Caenorhabditis elegans lin-39, mab-5 and egl-5 Hox genes specify cell fates along the anterior-posterior body axis of the nematode during postembryonic development, but little is known about Hox...
Journal Articles
Miguel Manzanares,, Sabine Cordes,, Linda Ariza-McNaughton,, Virginia Sadl,, Kamala Maruthainar,, Greg Barsh, Robb Krumlauf
Journal:
Development
Development (1999) 126 (4): 759–769.
Published: 15 February 1999
...Miguel Manzanares,; Sabine Cordes,; Linda Ariza-McNaughton,; Virginia Sadl,; Kamala Maruthainar,; Greg Barsh; Robb Krumlauf During anteroposterior patterning of the developing hindbrain, the anterior expression of 3′ Hox genes maps to distinct rhombomeric boundaries and, in many cases...
Journal Articles
Journal:
Development
Development (1999) 126 (4): 805–814.
Published: 15 February 1999
...Craig P. Hunter; Jeanne M. Harris; Julin N. Maloof; Cynthia Kenyon In Caenorhabditis elegans males, a row of epidermal precursor cells called seam cells generates a pattern of cuticular alae in anterior body regions and neural sensilla called rays in the posterior. The Hox gene mab-5 is required...
Journal Articles
Journal:
Development
Development (1999) 126 (1): 37–49.
Published: 1 January 1999
...Julin N. Maloof; Jennifer Whangbo; Jeanne M. Harris; Gregg D. Jongeward; Cynthia Kenyon ABSTRACT The specification of body pattern along the anteroposterior (A/P) body axis is achieved largely by the actions of conserved clusters of Hox genes. Limiting expression of these genes to localized...
Journal Articles
Journal:
Development
Development (1997) 124 (16): 3135–3146.
Published: 15 August 1997
...Alastair Morrison; Linda Ariza-McNaughton; Alex Gould; Mark Featherstone; Robb Krumlauf ABSTRACT From an evolutionary perspective, it is important to understand the degree of conservation of cis -regulatory mechanisms between paralogous Hox genes. In this study, we have used transgenic analysis...
Journal Articles
Journal:
Development
Development (1996) 122 (10): 3117–3131.
Published: 1 October 1996
...Jeanne Harris; Lee Honigberg; Naomi Robinson; Cynthia Kenyon ABSTRACT In C. elegans , the Hox gene mab-5 , which specifies the fates of cells in the posterior body region, has been shown to direct the migrations of certain cells within its domain of function. mab-5 expression switches...
Journal Articles
Journal:
Development
Development (1996) 122 (7): 2143–2152.
Published: 1 July 1996
... significant homeobox-containing genes ( McGinnis and Krumlauf, 1992 ). Each rhombomere can thus be characterised by a specific repertoire of Hox gene expression and a clonally restricted population of dividing neuroepithelial cells, arguing that the rhombomeres are specification units. By contrast...
Journal Articles
Journal:
Development
Development (1996) 122 (5): 1651–1661.
Published: 1 May 1996
...Stephen J. Salser; Cynthia Kenyon ABSTRACT Hox genes establish body pattern throughout the animal kingdom, but the role these genes play at the cellular level to modify and shape parts of the body remains a mystery. We find that the C. elegans Antennapedia homolog, mab-5 , sequentially programs...
Journal Articles
Journal:
Development
Development (1995) 121 (10): 3197–3205.
Published: 1 October 1995
.... Here, we investigated expression of the ascidian labial group Hox gene HrHox-1 in the development of Halo-cynthia roretzi. HrHox-1 showed a spatially restricted expression pattern along the anterior-posterior axis, which is remarkably similar to that of the vertebrate gene, Hoxb-1 . The expression...
Journal Articles
Journal:
Development
Development (1994) 1994 (Supplement): 163–168.
Published: 1 January 1994
... (and the fins of the Crossopterygians) in terms of developmental mechanisms? © 1994 by Company of Biologists 1994 limb development palaeontogeny Hox gene tetrapod The developmental basis of macroevolution has long been ignored by the neo-Darwinian synthesis, with its emphasis...
Journal Articles
Journal:
Development
Development (1994) 1994 (Supplement): 181–186.
Published: 1 January 1994
... genes may be different in these early and late roles. The combined action of many Hox genes on distinct developmental processes contribute to pattern asymmetry along the A-P axis. © 1994 by Company of Biologists 1994 Hox gene limb bud morphogenesis axis specification anteroposterior...
Journal Articles
Journal:
Development
Development (1994) 1994 (Supplement): 169–180.
Published: 1 January 1994
.... Transformational sequences apparent from the fish tetrapod transition are reiterated among extant lungfishes, indicating further directions for comparative experimental research. The evolutionary diversification of vertebrate fin and limb patterns challenges a simple linkage between Hox gene conservation...
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