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Keywords: Homeotic transformationsClose
Anna M. Raines, Mike Adam, Bliss Magella, Sara E. Meyer, H. Leighton Grimes, Sudhansu K. Dey, S. Steven Potter
Development (2013) 140 (14): 2942–2952.
Published: 15 July 2013
..., we describe the use of a novel recombineering strategy to introduce simultaneous frameshift mutations into the flanking Hoxa9, Hoxa10 and Hoxa11 genes, as well as their paralogs on the HoxD cluster. The resulting Hoxa9,10,11 mutant mice displayed dramatic synergistic homeotic transformations...
Includes: Supplementary data
Suzan Abu-Abed, Pascal Dollé, Daniel Metzger, Caroline Wood, Glenn MacLean, Pierre Chambon, Martin Petkovich
Development (2003) 130 (7): 1449–1459.
Published: 1 April 2003
... downregulation of WNT3A and FGF8 signaling pathways by eliminating ectopic RA in gastrulating tail bud mesoderm. Gastrulation Tail bud Cytochrome P450 Homeotic transformations Mouse mutant Retinoids Retinoic acid Teratogenesis Spina bifida Caudal regression Cyp26a1 RARγ Wnt3a Brachyury...