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Keywords: Hereditary multiple exostoses
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Journal Articles
Journal: Development
Development (2005) 132 (22): 5055–5068.
Published: 15 November 2005
...Dominique Stickens; Beverly M. Zak; Nathalie Rougier; Jeffrey D. Esko; Zena Werb Hereditary multiple exostoses (HME) is a genetically heterogeneous human disease characterized by the development of bony outgrowths near the ends of long bones. HME results from mutations in EXT1 and EXT2 ,genes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 1927–1938.
Published: 1 May 2004
... Decapentaplegic Tout velu Sister of tout velu Hereditary multiple exostoses EXT1 EXT2 There is mounting evidence that extracellular proteoglycans critically affect the signaling efficiency of secreted growth factors by modulating ligand stability, transport and ligand-receptor interaction...