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Keywords: Heart hypertrophyClose
Maria Sibilia, Bettina Wagner, Astrid Hoebertz, Candace Elliott, Silvia Marino, Wolfram Jochum, Erwin F. Wagner
Development (2003) 130 (19): 4515–4525.
Published: 1 October 2003
... is fully rescued in hEGFR KI/KI mice, however, they develop a severe heart hypertrophy with semilunar valve abnormalities. Moreover, hEGFR KI/KI mice display accelerated chondrocyte and osteoblast differentiation, a phenotype that is also present in Egfr -/- mice and has not been previously described...