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Keywords: HLH-2
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Journal Articles
Journal: Development
Development (2020) 147 (1): dev185850.
Published: 2 January 2020
... that promotes cell invasion. The anchor cell is initially specified in a stochastic cell fate decision mediated by Notch signaling. Previous research has identified four conserved transcription factors, fos-1 (Fos), egl-43 (EVI1/MEL), hlh-2 (E/Daughterless) and nhr-67 (NR2E1/TLX), that mediate anchor cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (4): 669–679.
Published: 15 February 2007
... specification at an early developmental stage, and functions downstream of fos-1 as well as upstream of zmp-1 and him-4 to regulate AC invasion at a later developmental stage. Characterization of the egl-43 regulatory region suggests that EGL-43 is a direct target of LIN-12 and HLH-2(E12/47), which is required...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (1): 143–151.
Published: 1 January 2004
... indicate that distinct trans-acting factors,including the E-protein/Daughterless homolog HLH-2 and unidentified nuclear hormone receptor(s), are necessary for lin-3 transcription in the AC and thus are involved in vulval development. References Asahina, M., Ishihara, T., Jindra, M., Kohara, Y...
Journal Articles
Journal: Development
Development (2003) 130 (26): 6507–6518.
Published: 29 December 2003
... aspects of metazoan development, can control cell fate choices in C. elegans by regulating asymmetric cell divisions. Finally, a reduction in the function of hlh-2 , which encodes the C. elegans E/Daughterless bHLH homolog, results in similar neuron loss as hlh-14 mutants and enhances the effects...