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In collection:Neural development
Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Hiroki Kobayashi, Laura Vrbanac, Jia Q. Ng, Josephine A. Wright, Tamsin R. M. Lannagan, Krystyna A. Gieniec, Martin Lewis, Ryota Ando, Atsushi Enomoto, Simon Koblar, Paul Thomas, Daniel L. Worthley, Susan L. Woods
Development (2021) 148 (14): dev195883.
Published: 12 July 2021
...) signaling is required for early forebrain development and cortical formation. How the endogenous modulators of BMP signaling regulate the structural and functional maturation of the developing brain remains unclear. Here, we show that expression of the BMP antagonist Grem1 marks committed layer V and VI...
Includes: Supplementary data
Development (2004) 131 (14): 3401–3410.
Published: 15 July 2004
... that the BMP antagonist gremlin ( Grem1 ) is essential to initiate these epithelial-mesenchymal signaling interactions during limb and metanephric kidney organogenesis. A Grem1 null mutation in the mouse generated by gene targeting causes neonatal lethality because of the lack of kidneys and lung septation...