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Keywords: Gonadogenesis
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Journal Articles
Journal: Development
Development (2015) 142 (13): 2268–2277.
Published: 1 July 2015
... genetic and lineage tracing data demonstrated that a subset of SGPs is Notch-activated early during gonadogenesis ( Okegbe and DiNardo, 2011 ). Several hours later, these cells assemble into a compact niche that expresses various factors required for stem cell recruitment, attachment and self-renewal ( Le...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (9): 1687–1696.
Published: 1 May 2011
.... In contrast to a previous report, we did not observe significant conversion of steady-state CySC progeny to hub fate. However, we found that these two cell types derive from a common precursor pool during gonadogenesis. Furthermore, lines mutant embryos exhibited gonads containing excess hub cells, indicating...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (7): 1259–1267.
Published: 1 April 2011
... induction. Last, perhaps during later stages of gonadogenesis (stages 14-16) a small number of anterior SGPs become Notch activated due to the activity of Serrate-Notch signaling from other SGPs, supplementing the hub cells previously specified by Delta-Notch signaling. Given that niche cells...
Journal Articles
Journal: Development
Development (2009) 136 (23): 3907–3915.
Published: 1 December 2009
... for male gonadogenesis of C. elegans . During the L3 and L4 larval stages of wild-type males, the LC undergoes changes in its position along the migratory route, in transcriptional regulation of the unc-5 netrin receptor and zmp-1 zinc matrix metalloprotease, and in cell morphology. We have identified...
Journal Articles
Journal: Development
Development (2004) 131 (17): 4333–4343.
Published: 1 September 2004
... are sexually transformed from hermaphrodite to male ( Meyer,1997 ). In addition, tra-1 affects gonadogenesis: 20-50%of both XX and XO null mutants possess small and variably mis-shapen gonads( Hodgkin, 1987 ; Schedl et al., 1989 ). However,the role of tra-1 in gonadogenesis had not been explored...
Journal Articles
Journal: Development
Development (2004) 131 (16): 4095–4105.
Published: 15 August 2004
.... and Capel, B. ( 1997 ). Male-specific cell migration into the developing gonad. Curr. Biol. 7 , 958 -968. Mathies, L. D., Henderson, S. T. and Kimble, J. ( 2003 ). The C. elegans Hand gene controls embryogenesis and early gonadogenesis. Development 130 , 2881 -2892. McLaren, A. ( 1991...
Journal Articles
Journal: Development
Development (2004) 131 (12): 2865–2874.
Published: 15 June 2004
... Biology, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-Ku, Yokohama 236-0004, Japan 26 2 2004 © 2004. 2004 Cell polarity Ovulation Gonadogenesis Caenorhabditis elegans Acquisition of cell polarity is important to epithelial cells for carrying out...
Journal Articles
Journal: Development
Development (2004) 131 (6): 1425–1436.
Published: 15 March 2004
... fkh-6 reporter is gonad-specific. Genetic and molecular analyses place fkh-6 downstream of tra-1 , the terminal regulator of the global sex determination pathway, with respect to the first gonadal cell division. We conclude that fkh-6 regulates gonadogenesis in both sexes, but is male specific...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2881–2892.
Published: 1 July 2003
...Laura D. Mathies; Samuel T. Henderson; Judith Kimble The C. elegans genome encodes a single Hand bHLH transcription factor. Either hnd-1(RNAi) or a hnd-1 deletion causes partially penetrant defects in viability and gonadogenesis. Dead embryos and young larvae are often misshapen at the posterior...
Journal Articles
Journal: Development
Development (2002) 129 (2): 443–453.
Published: 15 January 2002
...Kellee R. Siegfried; Judith Kimble The shape and polarity of the C. elegans gonad is defined during early gonadogenesis by two somatic gonadal precursor cells, Z1 and Z4, and their descendants. Z1 and Z4 divide asymmetrically to establish the proximal-distal axes of the gonad and to generate...
Journal Articles
Journal: Development
Development (1985) 90 (1): 13–32.
Published: 1 December 1985
...H. K. Parmentier; L. P. M. Timmermans Gonadal development, germ cell differentiation and the appearance of membrane antigenic determinants, specific for male and female germ cells during gonadogenesis, was studied in larval and juvenile carp ( Cyprinus carpio L.) until 25 weeks after fertilization...