... in chromatin organisation changes without effects on expression patterns or phenotypes, suggesting that Shh developmental regulation is robust to TAD perturbations. Chromosome conformation capture Fluorescence in situ hybridisation Shh Enhancers Genome organisation Development Topologically...

... tracks representing different features or calculated with different parameters (as discussed below). Discrete features, such as ChIP-seq peaks or gene annotations, are typically represented as blocks on a linear track. This approach is also used for some discrete features of genome organisation...