1-20 of 40
Keywords: Gene regulatory network
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2022) 149 (5): dev199632.
Published: 9 March 2022
...Shannon E. Taylor; Peter K. Dearden ABSTRACT Insect segmentation is a well-studied and tractable system with which to investigate the genetic regulation of development. Though insects segment their germband using a variety of methods, modelling work implies that a single gene regulatory network can...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (24): dev199779.
Published: 22 December 2021
...Megan K. Rommelfanger; Adam L. MacLean ABSTRACT Cells do not make fate decisions independently. Arguably, every cell-fate decision occurs in response to environmental signals. In many cases, cell-cell communication alters the dynamics of the internal gene regulatory network of a cell to initiate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (9): dev198549.
Published: 30 April 2021
....21856 Souferi , B. and Emerson , M. M. ( 2019 ). Quantitative analysis of the ThrbCRM1-centered gene regulatory network . Biol. Open 8 , bio039115 . 10.1242/bio.039115 Suzuki , S. C. , Bleckert , A. , Williams , P. R. , Takechi , M. , Kawamura , S...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev197566.
Published: 25 February 2021
...Katherine Exelby; Edgar Herrera-Delgado; Lorena Garcia Perez; Ruben Perez-Carrasco; Andreas Sagner; Vicki Metzis; Peter Sollich; James Briscoe ABSTRACT During development, gene regulatory networks allocate cell fates by partitioning tissues into spatially organised domains of gene expression. How...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (2): dev189944.
Published: 20 January 2021
...-ventral axis specification in sea urchin embryos, highlighting key features of Nodal and BMP antagonism. Paracentrotus lividus Embryo development Logical model Gene regulatory network Nodal pathway BMP pathway During embryonic development, cell fate is specified by transcription...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2020) 147 (8): dev186130.
Published: 20 April 2020
... is under robust, complex control. We found that one candidate regulator, the G-class bZIP transcription factor GBF2, can modulate vascular gene expression by tuning MP output through direct interaction. Our work uncovers components of a gene regulatory network that controls the initial specification...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (5): dev182576.
Published: 12 March 2020
... variant upstream of the core gene regulatory network in the neural crest lineage. This epigenetic mark is a key determinant of cell fate and facilitates gene activation by external instructive signals, thereby establishing melanocyte fate identity. Fish experiments were performed in strict accordance...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (3): dev184432.
Published: 5 February 2020
... transcription defines a gene regulatory network for cardiac rhythm . eLife   6 , e31683 . 10.7554/eLife.31683 Yoshida , S. , Mears , A. J. , Friedman , J. S. , Carter , T. , He , S. , Oh , E. , Jing , Y. , Farjo , R. , Fleury , G. , Barlow , C. , et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (1): dev185850.
Published: 2 January 2020
...Taylor N. Medwig-Kinney; Jayson J. Smith; Nicholas J. Palmisano; Sujata Tank; Wan Zhang; David Q. Matus ABSTRACT Cellular invasion is a key part of development, immunity and disease. Using an in vivo model of Caenorhabditis elegans anchor cell invasion, we characterize the gene regulatory network...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (22): dev182154.
Published: 25 November 2019
... in discrete domains along the dorsal-ventral and anterior-posterior axes of the embryonic spinal cord. This organization arises in response to morphogen gradients acting upstream of a gene regulatory network, the architecture of which determines the spatial and temporal pattern of gene expression. In recent...
Journal Articles
Journal: Development
Development (2019) 146 (16): dev180653.
Published: 19 August 2019
.../user-licence-1-1/ Summary: ChIP-seq provides a genome-wide view of the binding sites of Alx1, a pivotal transcription factor in a gene regulatory network that controls skeletogenesis in sea urchins and other echinoderms. Alx1 transcription factor ChIP-seq Gene regulatory network Sea...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev173104.
Published: 4 February 2019
... understanding of the regulatory pathway is essential for accurate modeling in order to deduce principles for gene regulatory network dynamics, and for comparative analysis on how ascidians have evolved the cell-autonomous gene regulatory mechanism. Here, we reveal regulatory interactions among three key...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev165985.
Published: 2 July 2018
... repressor Yan and the co-repressor Groucho by the transcriptional activator Pointed confers precision and robustness to the gene expression dynamics that drive developmental cell fate transitions. Gene regulatory network Cell fate specification Chromatin occupancy Mesoderm development RNA pol II...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (10): dev155580.
Published: 23 May 2018
...’ insect species ( Krause, 1939 ; Sander, 1976 ; Davis and Patel, 2002 ; Liu and Kaufman, 2005 ), even though the insect body plan is largely invariant. Drosophila Gene regulatory network Pair-rule genes Patterning Segmentation Tribolium Highlighted Article: Caudal, Dichaete...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (9): dev157081.
Published: 30 April 2018
... of the STM gene regulatory network (GRN) are largely unknown. Here, we show that transcriptional regulators are overrepresented among STM-regulated genes and, using these as GRN components in Bayesian network analysis, we infer STM GRN associations and reveal regulatory relationships between STM and factors...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (3): dev159707.
Published: 8 February 2018
... that fine-tunes the extent of root hair growth by the orchestrated actions of opposing transcription factors. Root hair Cell growth Trihelix transcription factor Gene regulatory network Plant cells often undergo extensive post-mitotic cell expansion and can reach up to several hundred-fold...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4214–4225.
Published: 1 December 2017
... of developmental processes such as molecular patterning and tissue morphogenesis, highlighting their advantages and limitations, and their crucial role in future research. Computer modeling Simulation Developmental biology Morphogenesis Gene regulatory network Gene circuit D'Arcy Thompson's...
Journal Articles
Journal: Development
Development (2017) 144 (19): 3487–3498.
Published: 1 October 2017
...Jonathon T. Hill; Bradley Demarest; Bushra Gorsi; Megan Smith; H. Joseph Yost During embryogenesis the heart forms as a linear tube that then undergoes multiple simultaneous morphogenetic events to obtain its mature shape. To understand the gene regulatory networks (GRNs) driving this phase...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (15): 2810–2823.
Published: 1 August 2017
... the induction and patterning of chick sensory placodes. Chick embryo Quail graft Cell fate Sense organs Sensory ganglia Transcriptional networks Signalling Gene regulatory network During early development, many fate decisions are controlled by inductive interactions, whereby an inducing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1363–1374.
Published: 15 April 2016
... and enteric nervous system development by, at least in part, directly controlling the expression of the key early regulators of NC ontogenesis Pax3 , Msx1 and Foxd3 . Our work thus reveals a novel role for Cdx proteins at the top of the trunk NC gene regulatory network in the mouse, which appears to have been...
Includes: Supplementary data