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Keywords: Gene regulatory network
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Journal Articles
Journal: Development
Development (2023) 150 (22): dev201804.
Published: 27 November 2023
... embryo. Echinoderm Sea urchin Skeletogenesis Primary mesenchyme Syncytium Gene regulatory network National Science Foundation http://dx.doi.org/10.13039/100000001 IOS2004952 Multinucleated cells, also known as syncytia, are found across the tree of life ( Ogle et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (22): dev201016.
Published: 16 November 2022
.../10.13039/100000057 Rutgers, The State University of New Jersey http://dx.doi.org/10.13039/100011132 Developmental genes Anterior-posterior axis coordination Genes tagging Gene regulatory network Shared enhancers Cis -regulation Summary: CRISPR/Cas9 genome editing reveals...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200667.
Published: 28 October 2022
.... ( 2012 ). Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks . Dev. Cell 23 , 637 - 651 . 10.1016/j.devcel.2012.07.008 Peterson , R. S. , Lim , L. , Ye , H. , Zhou , H. , Overdier , D. G. and Costa , R. H...
Includes: Supplementary data
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Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (24): dev199779.
Published: 22 December 2021
...Megan K. Rommelfanger; Adam L. MacLean ABSTRACT Cells do not make fate decisions independently. Arguably, every cell-fate decision occurs in response to environmental signals. In many cases, cell-cell communication alters the dynamics of the internal gene regulatory network of a cell to initiate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (9): dev198549.
Published: 30 April 2021
... to the dysfunction, and sometimes the death, of these photoreceptors ( Campochiaro and Mir, 2018 ; https://sph.uth.edu/retnet/ ). As cones are the type of photoreceptor that we use to initiate color and daylight vision, their loss can be devastating. A better understanding of the gene regulatory networks (GRNs...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (2): dev189944.
Published: 20 January 2021
... the dorsal-ventral axis specification in sea urchin embryos, highlighting key features of Nodal and BMP antagonism. Paracentrotus lividus Embryo development Logical model Gene regulatory network Nodal pathway BMP pathway During embryonic development, cell fate is specified...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2020) 147 (8): dev186130.
Published: 20 April 2020
... is under robust, complex control. We found that one candidate regulator, the G-class bZIP transcription factor GBF2, can modulate vascular gene expression by tuning MP output through direct interaction. Our work uncovers components of a gene regulatory network that controls the initial specification...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (5): dev182576.
Published: 12 March 2020
... variant upstream of the core gene regulatory network in the neural crest lineage. This epigenetic mark is a key determinant of cell fate and facilitates gene activation by external instructive signals, thereby establishing melanocyte fate identity. Across vertebrates, the histone variant H2A.Z...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (3): dev184432.
Published: 5 February 2020
... in the developing mouse retina. Enhancer Transcription factor Non-coding RNA (ncRNA) Photoreceptor Nrl Crx Rod Cone Gene regulatory network Cis -regulatory element Identification of tissue- and context-specific cis -regulatory elements (CREs) is essential for the definition...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (22): dev182154.
Published: 25 November 2019
... in discrete domains along the dorsal-ventral and anterior-posterior axes of the embryonic spinal cord. This organization arises in response to morphogen gradients acting upstream of a gene regulatory network, the architecture of which determines the spatial and temporal pattern of gene expression. In recent...
Journal Articles
Journal: Development
Development (2019) 146 (16): dev180653.
Published: 19 August 2019
... regulatory network that controls skeletogenesis in sea urchins and other echinoderms. Alx1 transcription factor ChIP-seq Gene regulatory network Sea urchin skeletogenesis Biomineralization Primary mesenchyme cells (PMCs) A central challenge of biology is to explain how morphology...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev173104.
Published: 4 February 2019
... understanding of the regulatory pathway is essential for accurate modeling in order to deduce principles for gene regulatory network dynamics, and for comparative analysis on how ascidians have evolved the cell-autonomous gene regulatory mechanism. Here, we reveal regulatory interactions among three key...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (10): dev155580.
Published: 23 May 2018
.... Dyn.   242 , 897 - 908 . 10.1002/dvdy.23978 Chipman , A. D. ( 2010 ). Parallel evolution of segmentation by co-option of ancestral gene regulatory networks . BioEssays   32 , 60 - 70 . 10.1002/bies.200900130 Choe , C. P. and Brown , S. J. ( 2007 ). Evolutionary...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (9): dev157081.
Published: 30 April 2018
... of the STM gene regulatory network (GRN) are largely unknown. Here, we show that transcriptional regulators are overrepresented among STM-regulated genes and, using these as GRN components in Bayesian network analysis, we infer STM GRN associations and reveal regulatory relationships between STM and factors...
Includes: Supplementary data
Journal Articles