...Katsiaryna Maskalenka; Gökberk Alagöz; Felix Krueger; Joshua Wright; Maria Rostovskaya; Asif Nakhuda; Adam Bendall; Christel Krueger; Simon Walker; Aylwyn Scally; Peter J. Rugg-Gunn ABSTRACT Gene duplication events can drive evolution by providing genetic material for new gene functions...

...Susanna Streubel; Michael André Fritz; Melanie Teltow; Christian Kappel; Adrien Sicard ABSTRACT Gene duplication is a major driver for the increase of biological complexity. The divergence of newly duplicated paralogs may allow novel functions to evolve, while maintaining the ancestral one...

...@uottawa.ca ) 5 9 2008 © 2008. 2008 CNS development Gene duplication Mouse embryogenesis Transcriptional regulation Zebrafish embryogenesis cis-acting regulatory elements Duplication events, which can affect anything from single genes to the whole genome, are thought...

...-specific gene duplication. We show that both paralogues acquired novel functions, both at the level of their cis-regulation as well as through significant divergence of the coding sequence. Both genes are expressed in the hypostome, but HyBra1 is predominantly endodermal, whereas HyBra2 transcripts...

... 22 12 2004 ©2005. 2005 Chondrogenesis Craniofacial Gene duplication Genome duplication Limb morphogenesis Skeletogenesis Subfunction partitioning Conserved genetic pathways control development of chordate features (e.g. Bassham and Postlethwait, 2000 ; Satoh, 2003...

... Gene duplication orbiter Sensory receptors in the ear and eye are thought to have evolved from a common ancestral ciliated cell (reviewed by Popper et al., 1992 ). Both receptors have highly specialized apical surfaces. Receptor cells in the ear possess an apical bundle of actin-filled...

... at the end of the manuscript 20 10 2004 © 2004. 2004 Zebrafish Hematopoiesis Transferrin receptor Iron Gene duplication Iron acquisition by developing erythroid cells is necessary to produce hemoglobin, which allows red blood cells to deliver oxygen to body tissues...

.... C. ( 1998 ). Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev. Biol . 199 , 93 -110. Ohno, S. ( 1970 ). Evolution by Gene Duplication . New York: Springer-Verlag. Oxtoby, E...

... of Biologists 1998 Slug, Snail Mouse Chick Zinc-finger transcription factor Neural crest Mesoderm Gene duplication Chordate Vertebrate Evolution Much of the progress made in our understanding of developmental processes over recent years has been the result of the identification...

... that are again unique to vertebrates. We are interested in the genetic changes that may have permitted the origin of these inno vations. Gene duplication, followed by functional diver gence of new genes, may be one class of mutation that permits major evolutionary change. Here we examine the hypothesis that gene...