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Keywords: Gap junctions
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Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (15): 2598–2609.
Published: 1 August 2015
..., Hedgehog, BMP and EGF pathways are used to mediate soma-germline communication. Here, we demonstrate that gap junctions may also mediate direct, bi-directional signalling between the soma and germ line. When gap junctions between the soma and germ line are disrupted, germline differentiation is blocked...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (11): 1869–1878.
Published: 1 June 2009
... signal from the somatic cells is cGMP. Using FRET-based cyclic nucleotide sensors in follicle-enclosed mouse oocytes, we find that cGMP passes through gap junctions into the oocyte,where it inhibits the hydrolysis of cAMP by the phosphodiesterase PDE3A. This inhibition maintains a high concentration...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2000) 127 (19): 4179–4193.
Published: 1 October 2000
...Olaf Krüger; Achim Plum; Jung-Sun Kim; Elke Winterhager; Stephan Maxeiner; Gaby Hallas; Susanne Kirchhoff; Otto Traub; Wouter H. Lamers; Klaus Willecke ABSTRACT In order to reveal the biological function(s) of the gap-junction protein connexin 45 (Cx45), we generated Cx45 -deficient mice...
Journal Articles
Journal: Development
Development (1992) 116 (3): 639–651.
Published: 1 November 1992
...Boris Risek; F. George Klier; Norton B. Gilula ABSTRACT The expression of four different gap junction gene products ( α 1 , β 1 , β 2 , andβ 3 ) has been analysed during rat skin development and the hair growth cycle. Both α 1 (C×43) and β 2 (C×26) connexins were coexpressed in the undifferentiated...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 114 (2): 389–393.
Published: 1 February 1992
... be related to previous ultrastructural studies by others on the distribution of gap junctions in the wool follicle. These results show that junctional communication, with its consequent intercellular spread of small ions and molecules, is associated with uniformity of expression and behaviour within cell...
Journal Articles
Journal: Development
Development (1991) 112 (1): 153–160.
Published: 1 May 1991
..., since we did not observe any significant number of cytoplasmic bridges at the EM and G j is sensitive to octanol, it is probable that blastomeres in the 2-cell and 32-cell embryos are in communication by gap junctions. In order to compare G j in the two stages and to circumvent problems of cell size...
Journal Articles
Journal: Development
Development (1990) 108 (4): 623–634.
Published: 1 April 1990
...Francesca Allen; Cheryll Tickle; Anne Warner The role of gap junctional communication during patterning of the chick limb has been investigated. Affinity-purified antibodies raised against rat liver gap junctional proteins were used to block communication between limb mesenchyme cells. Co-injection...
Journal Articles
Journal Articles
Journal: Development
Development (1986) 91 (1): 283–296.
Published: 1 February 1986
...Harry Goodall ABSTRACT Three treatments that prevent cell flattening during compaction of the mouse preimplantation embryo were assessed for their effects on the onset of gap junctional communication. Medium low in calcium (LCM) and an antiserum to an embryonal carcinoma cell line (anti-EC; Johnson...
Journal Articles
Journal: Development
Development (1985) 89 (Supplement): 365–380.
Published: 1 November 1985
...Anne E. Warner ABSTRACT The possibility that communication through gap junctions may be important during embryonic development has often been raised since gap junctions were first described between early embryonic cells. It is now known that this direct cell-to-cell communication pathway disappears...