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Keywords: GSK-3
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Journal Articles
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Neural development
Journal: Development
Development (2019) 146 (20): dev177550.
Published: 10 October 2019
... medulloblastoma, the most common malignant pediatric brain tumor. Although sonic hedgehog (SHH) signaling is known to activate CGNP proliferation, the mechanisms downregulating proliferation are less defined. We investigated CGNP regulation by GSK-3, which downregulates proliferation in the forebrain, gut...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 325–334.
Published: 15 January 2012
... factor required for ac-sc expression, the expression of which coincides temporally with that of ac-sc in the notum, is Wingless (Wg; also known as Wnt). Wingless downregulates the activity of the serine/threonine kinase Shaggy (Sgg; also known as GSK-3). We demonstrate that Scute is phosphorylated by Sgg...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4555–4565.
Published: 15 September 2004
... gskA for optimal expression. These observations show that GskA functions throughout Dictyostelium development, to regulate several key aspects of cellular patterning. * Author for correspondence (e-mail: j.g.williams@dundee.ac.uk ) 22 6 2004 © 2004. 2004 GSK-3 Dictyostelium...