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Keywords: GPCR
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Journal Articles
Journal: Development
Development (2021) 148 (5): dev196667.
Published: 10 March 2021
... (GPCRs); however, the underlying mechanisms are unclear. Here, we show that a newly discovered ecdysone-responsive GPCR, ErGPCR-3, transmits the steroid hormone 20-hydroxyecdysone (20E) signal by binding 20E and promoting its entry into cells in the lepidopteran insect Helicoverpa armigera . Knockdown...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (8): 1390–1395.
Published: 15 April 2015
... al., 2014 ). These seven-transmembrane GPCRs bind different forms of LPA with varying affinities and activate specific heterotrimeric G protein pathways defined, in part, by Gα 12/13 , Gα q/11 , Gα i/o and Gα s . The downstream signalling cascades involve well-known mediators such as Ras, Rho, Rac...
Journal Articles
Journal: Development
Development (2014) 141 (22): 4199–4205.
Published: 15 November 2014
... used to guide migrating cells. * Author for correspondence ( holger.knaut@med.nyu.edu ) Competing interests The authors declare no competing financial interests. © 2014. Published by The Company of Biologists Ltd 2014 GPCR Cell migration Chemokine CXCL12 CXCR4...
Journal Articles
Journal: Development
Development (2010) 137 (21): 3663–3673.
Published: 1 November 2010
... in pioneers and followers. * Author for correspondence ( hutter@sfu.ca ) Competing interests statement 2 9 2010 © 2010. Axon guidance flamingo C. elegans Pioneer Follower Nervous system Cadherin Adhesion GPCR The creation of a functional...
Journal Articles
Journal: Development
Development (2007) 134 (14): 2651–2661.
Published: 15 July 2007
.... † Author for correspondence (e-mail: Christopher.Wylie@cchmc.org ) * These authors contributed equally to this work 8 5 2007 © 2007. 2007 Cortical actin Actin assembly Xenopus GPCR Cadherins C-cadherin p120 catenin Xflop LPA The Xenopus blastula is a hollow...
Journal Articles
Journal: Development
Development (2007) 134 (13): 2459–2468.
Published: 1 July 2007
.... * Author for correspondence (e-mail: miyasaka@brain.riken.jp ) 12 4 2007 © 2007. 2007 Stromal cell-derived factor-1 (SDF-1) GPCR Cell migration Axon guidance Pioneer axons Zebrafish Cell positioning and axon pathfinding are developmental processes crucial for the formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (11): 2253–2261.
Published: 1 June 2006
... is not only a neurotransmitter but also an ancient intercellular signal. * Author for correspondence (e-mail: wloomis@ucsd.edu ) 7 4 2006 © 2006. 2006 gadA GrlE SDF-2 Sporulation GPCR The efficiency and timing of sporulation in Dictyostelium discoideum...