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Keywords: Foxa1
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Journal Articles
Journal: Development
Development (2021) 148 (15): dev199754.
Published: 29 July 2021
... for survival and progression. We show that the pioneer transcription factors Foxa1 and Foxa2 are required to regulate RNA splicing during positive selection of mouse T cells and that Foxa1 and Foxa2 have overlapping/compensatory roles. Conditional deletion of both Foxa1 and Foxa2 from DP thymocytes reduced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (6): dev192401.
Published: 24 March 2021
... there is compensatory upregulation of Grg4 . Grg3/4 double mutant mice have severe dysregulation of the pancreas gene program with ectopic expression of canonical liver genes and Foxa1 , a master regulator of the liver program. Neurod1 , an essential β cell transcription factor and predicted target of Foxa1 , becomes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (20): 3519–3528.
Published: 15 October 2015
..., differential Foxa1/Foxa2 expression distinguished two spatially separated pools of C cell precursors with different growth properties. A similar expression pattern was recapitulated in medullary thyroid carcinoma cells in vivo , consistent with a growth-promoting role of Foxa1. In contrast to embryonic...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (15): 3431–3443.
Published: 1 August 2005
...Nan Gao; Kenichiro Ishii; Janni Mirosevich; Satoru Kuwajima; Stacey R. Oppenheimer; Richard L. Roberts; Ming Jiang; Xiuping Yu; Scott B. Shappell; Richard M. Caprioli; Markus Stoffel; Simon W. Hayward; Robert J. Matusik We have previously shown that a forkhead transcription factor Foxa1 interacts...
Includes: Supplementary data