... localised within each cell. Dachsous Fat Four-jointed Frizzled Starry-night Van Gogh ‘ Polarity is in my mind the essential problem. We have to explain why one part of a cell becomes different from another part .’       Sydney Brenner (1994) Imagine how tricky it would...

... be eliminated when D/V patterning is disrupted and can be induced in situations in which ectopic boundaries are artificially generated. We also show that emc functions downstream of Notch signaling to maintain the expression of four-jointed along the midline. * Author for correspondence ( jkumar...

...José Casal; Peter A. Lawrence; Gary Struhl Planar polarity is a fundamental property of epithelia in animals and plants. In Drosophila it depends on at least two sets of genes: one set, the Ds system, encodes the cadherins Dachsous (Ds) and Fat (Ft), as well as the Golgi protein Four-jointed...

... that there is conserved binding to intracellular factors. * Author for correspondence (e-mail: ssblair@wisc.edu ) 27 3 2006 © 2006. 2006 Overgrowth Junction Four-jointed Dachs Frizzled Grunge Atrophin The Drosophila proteins Fat (Ft) and Dachsous (Ds) are required...

...Helen Strutt; Jenifer Mundy; Katrina Hofstra; David Strutt four-jointed ( fj ) is required for proximodistal growth and planar polarity in Drosophila tissues. It encodes a predicted type II transmembrane protein with putative signal peptidase sites in its transmembrane domain, and its C terminus...

... expression provides information about the strategies employed to subdivide and pattern the PD axis, and reveals the importance of vg during this process. Dve Vestigial/Scalloped Nubbin four-jointed Proximal wing Pattern formation Homeobox transcription factor The development...

...Gerri R. Buckles; Cordelia Rauskolb; John Lee Villano; Flora N. Katz The molecular basis of segmentation and regional growth during morphogenesis of Drosophila legs is poorly understood. We show that four-jointed is not only required for these processes, but also can direct ectopic growth and joint...