...Marika Kapsimali; Luca Caneparo; Corinne Houart; Stephen W. Wilson Ventral midline cells in the neural tube form floorplate throughout most of the central nervous system (CNS) but in the anterior forebrain, they differentiate with hypothalamic identity. The signalling pathways responsible...

... Notochord Floorplate Midline Left-right asymmetry Mouse Vertebrates are characterised by an external bilateral symmetry and an internal left-right (LR) asymmetry. This asymmetry is genetically determined and is crucial for the placement and orientation of internal organs. Failure...

...-Padilla, 1966 ). In addition to defective convergent extension and failed neural tube closure,human CRS is associated with bifurcated notochords, disorganized expression of SHH in the floorplate and bulging of the neural plate midline( Kirillova et al., 2000 ; Marin-Padilla, 1966 ; Saraga-Babic et al...

... immunocytochemistry to describe the spatiotemporal expression pattern of PSA during zebrafish central nervous system development. PSA is transiently expressed on all cell bodies and, except for the posterior commissure, it is not found on axons. Floorplate cells in the spinal cord and hindbrain strongly express PSA...