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Keywords: Floor plate
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Journal Articles
Journal: Development
Development (2018) 145 (2): dev150375.
Published: 17 January 2018
...Chloé Dominici; Quentin Rappeneau; Pavol Zelina; Stéphane Fouquet; Alain Chédotal ABSTRACT During development, precerebellar neurons migrate tangentially from the dorsal hindbrain to the floor plate. Their axons cross it but their cell bodies stop their ventral migration upon reaching the midline...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (5): 916–927.
Published: 01 March 2017
...Navid Nouri; Rajeshwar Awatramani The mesodiencephalic floor plate (mdFP) is the source of diverse neuron types. Yet, how this structure is compartmentalized has not been clearly elucidated. Here, we identify a novel boundary subdividing the mdFP into two microdomains, defined by engrailed 1 ( En1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (2): 244–254.
Published: 15 January 2016
... germ layer plasticity, these cells never give rise to midline tissues of the notochord, floor plate and dorsal endoderm, raising the question of whether midline tissues also arise from basal posterior progenitors after gastrulation. We show in zebrafish that local posterior signals specify germ layer...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (13): 2291–2303.
Published: 01 July 2015
... regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling . Development   137 , 4271 - 4282 . 10.1242/dev.051714 Dale , J. K. , Maroto , M. , Dequeant , M.-L. , Malapert , P. , McGrew , M. and Pourquie , O. ( 2003...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (6): 1392–1403.
Published: 15 March 2014
... ( Myers et al., 1986 ), sulf1 is upregulated in cells that already express shh and remains restricted to Shh source cells. Expression of shh is known to expand dorsally as development proceeds to form a novel ligand source, named the lateral floor plate (LFP) ( Charrier et al., 2002 ; Park et...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (3): 574–584.
Published: 01 February 2014
...Abed AlFatah Mansour; Sophie Khazanov-Zisman; Yaara Netser; Avihu Klar; Nissim Ben-Arie During embryogenesis, the dorsal roof plate and the ventral floor plate (FP) act as organizing centers to pattern the developing neural tube. Organizer-secreted morphogens provide signals that are interpreted...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2625–2634.
Published: 15 July 2012
...Emmanouil Metzakopian; Wei Lin; Mali Salmon-Divon; Heidi Dvinge; Elisabet Andersson; Johan Ericson; Thomas Perlmann; Jeffrey A. Whitsett; Paul Bertone; Siew-Lan Ang The transcription factors Foxa1 and Foxa2 promote the specification of midbrain dopaminergic (mDA) neurons and the floor plate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5121–5134.
Published: 01 December 2011
... equally to this work Competing interests statement The authors declare no competing financial interests. 4 10 2011 © 2011. Smoothened V1 V2 Floor plate Gli3 Interneuron Zebrafish In mouse, Hedgehog (Hh) signalling is required for the formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (12): 2613–2624.
Published: 15 June 2011
... study shows that a subset of anterior floor plate-like cells gives rise to Fgf3 + SOX3 + progenitor cells, demonstrates a dual origin of infundibular cells and reveals a crucial role for FGF signalling in governing extended infundibular growth. One likely early source of FGFs for the maintenance...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (23): 4051–4060.
Published: 01 December 2010
... patterning, and describe a feedback circuit between the Shh pathway and homeodomain transcription factors that establishes non-graded regulation of Shh signaling activity. Nkx2 proteins intrinsically strengthen Shh responses in a feed-forward amplification and are required for ventral floor plate and p3...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (11): 1807–1813.
Published: 01 June 2010
...Keiji Inohaya; Yoshiro Takano; Akira Kudo The floor plate is a key organizer that controls the specification of neurons in the central nervous system. Here, we show a new role of the floor plate: segmental pattern formation of the vertebral column. Analysis of a spontaneous medaka mutant, fused...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (4): 561–568.
Published: 15 February 2010
...Shona D. Gray; J. Kim Dale Hensen's node of the chick embryo contains multipotent self-renewing progenitor cells that can contribute to either the floor plate or the notochord. Floor plate cells are a population of epithelial cells that lie at the ventral midline of the developing neural tube...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (22): 3643–3653.
Published: 15 November 2008
... trajectories parallel to the floor plate. To identify longitudinal guidance mechanisms in vivo, the overall role of floor plate tissue and the specific roles of Slit/Robo signals were tested. Ectopic induction or genetic deletion of the floor plate diverted longitudinal axons into abnormal trajectories...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (13): 2467–2476.
Published: 01 July 2006
...@virus.kyoto-u.ac.jp ) * Present address: Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan 12 4 2006 © 2006. 2006 bHLH Floor plate Isthmus Rhombomere boundary Roof plate Zona limitans intrathalamica Mouse The developing...
Journal Articles
Journal: Development
Development (2006) 133 (12): 2395–2405.
Published: 15 June 2006
... Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai,Chiyoda-ku, Tokyo 101-0062, Japan 4 4 2006 © 2006. 2006 Xenopus Midline Cholesterol Floor plate Smith-Lemli-Opitz syndrome (SLOS) Sonic hedgehog The members...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 1035–1046.
Published: 01 March 2005
...Silvia L. López; María V. Rosato-Siri; Paula G. Franco; Alejandra R. Paganelli; Andrés E. Carrasco We have previously shown that the early Xenopus organiser contains cells equally potent to give rise to notochord or floor plate, and that Notch signalling triggers a binary decision, favouring...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4809–4821.
Published: 15 October 2003
...Iain Patten; Paul Kulesa; Michael M. Shen; Scott Fraser; Marysia Placzek To begin to reconcile models of floor plate formation in the vertebrate neural tube, we have performed experiments aimed at understanding the development of the early floor plate in the chick embryo. Using real-time analyses...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (16): 3891–3902.
Published: 15 August 2003
...Yongsu Jeong; Douglas J. Epstein The establishment of the floor plate at the ventral midline of the CNS is dependent on an inductive signaling process mediated by the secreted protein Sonic hedgehog (Shh). To understand molecularly how floor plate induction proceeds we identified a Shh-responsive...
Journal Articles
Journal: Development
Development (2003) 130 (14): 3331–3342.
Published: 15 July 2003
...Jing Tian; Caleb Yam; Gayathri Balasundaram; Hui Wang; Aniket Gore; Karuna Sampath The floor plate, a specialized group of cells in the ventral midline of the neural tube of vertebrates, plays crucial roles in patterning the central nervous system. Recent work from zebrafish, chick, chick-quail...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2225–2238.
Published: 15 May 2003
... the floor plate domain of sonic hedgehog and pintallavis and represses the notochordal markers chordin and brachyury, with a concomitant reduction of the notochord size. We propose that within a population of the early organiser with equivalent potential to develop either as notochord or floor plate, Notch...