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Keywords: Feedback
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Journal Articles
Journal: Development
Development (2011) 138 (4): 715–724.
Published: 15 February 2011
... it completes a novel auto-regulatory loop that modulates BMP activity. * Author for correspondence ( mg2@stowers.org ) Competing interests statement 22 11 2010 © 2011. BMP signaling DPP LTL Feedback Imaginal disc Morphogen Throughout multicellular...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (17): 2903–2911.
Published: 1 September 2009
... oogenesis, the two-domain expression pattern of Broad, a transcription factor essential for the formation of the two respiratory eggshell appendages, is established by a single gradient of EGFR activation that induces both Broad and Pointed, which mediates repression of Broad. Two negative-feedback loops...
Journal Articles
Journal: Development
Development (2008) 135 (18): 3021–3030.
Published: 15 September 2008
... between proneural proteins and Sina. As phyl is a direct transcriptional target of Ac and Sc, our data suggest that, in addition to mediating cell cycle arrest, proneural protein initiates a negative-feedback regulation to time the mitotic entry of neural precursors. Thus, our results indicate...
Journal Articles
Journal: Development
Development (2005) 132 (1): 143–154.
Published: 1 January 2005
... this response show surprisingly normal early development. The identification of Hh-interacting protein 1 (Hhip1), a vertebrate-specific feedback antagonist of Hh signaling, raises the possibility of overlapping feedback controls. We addressed the significance of feedback systems in sonic hedgehog(Shh)-dependent...
Includes: Supplementary data