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Keywords: Fate specification
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Journal Articles
Journal: Development
Development (2021) 148 (22): dev176057.
Published: 17 November 2021
...Robert N. Kelsh; Karen Camargo Sosa; Saeed Farjami; Vsevolod Makeev; Jonathan H. P. Dawes; Andrea Rocco ABSTRACT Neural crest cells are crucial in development, not least because of their remarkable multipotency. Early findings stimulated two hypotheses for how fate specification and commitment from...
Journal Articles
Journal: Development
Development (2016) 143 (19): 3573–3581.
Published: 1 October 2016
...Julia Kofent; Juan Zhang; Francesca M. Spagnoli Cell fate specification depends on transcriptional activation driven by lineage-specific transcription factors as well as changes in chromatin organization. To date, the interplay between transcription factors and chromatin modifiers during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (23): 4010–4025.
Published: 1 December 2015
... derived from individual blastomeres of 8- and 12-cell human embryos have unique properties, provide insights into early human embryogenesis and enable human trophoblast stem cell derivation. Human embryo Blastomere Human embryonic stem cell Human trophoblast stem cell Fate specification...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (19): 3286–3293.
Published: 1 October 2015
..., notably activator inputs mediated by Sox2, is probably a key mechanism in achieving cell type-specific transcriptional outcomes in mammalian neural progenitor fate specification. Open reading frames (ORF) were targeted to the engineered Hprt locus in the mA2.lox.Cre mESC line to express the ORFs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1267–1278.
Published: 1 April 2015
... interneurons Embryonic stem cells Fate specification Parvalbumin Somatostatin Sonic hedgehog Mouse In the mammalian neocortex, GABAergic cortical interneurons (cINs) facilitate cognition by providing inhibitory inputs to cortical circuitry ( Lehmann et al., 2012 ; Fino et al., 2013...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4619–4630.
Published: 1 December 2006
... have isolated a novel sox10 mutant that lacks glia and yet displays a neurogenic DRG phenotype. In conjunction with previous findings, these data establish the generality of our model of Sox10 function in NC fate specification. * Author for correspondence (e-mail: bssrnk@bath.ac.uk ) 21 9...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (13): 2969–2980.
Published: 1 July 2005
... (e-mail: amansou@gwdg.de ) 19 4 2005 ©2005. 2005 Endocrine pancreas development Arx Pax4 Mouse Hyperglycaemia Fate specification The pancreas plays a key role in the maintenance of nutritional homeostasis through the regulated synthesis and secretion of enzymes...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2917–2928.
Published: 1 July 2003
... (PMC) lineage of the sea urchin embryo is a model system for the analysis of fate specification, cell signaling,morphogenesis and biomineralization. PMCs are derived from the micromeres of the 16-cell stage embryo. At the fifth cleavage division, the micromeres divide unequally. The four large daughter...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2809–2818.
Published: 15 June 2003
... 2003 © 2003. 2003 Zebrafish Danio rerio Neural crest Fate specification Melanocyte sox10 colourless mitf nacre Survival Transcriptional regulation During vertebrate embryogenesis neural crest cells delaminate from the dorsal neural tube, migrate throughout...
Journal Articles
Journal: Development
Development (2001) 128 (17): 3269–3281.
Published: 1 September 2001
...-Gultekin, Z., Andachi Y., Tsalik E. L., Pilgrim, D., Kohara Y. and Hobert, O. ( 2001 ) A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans. Development 128 , 1951 -1969. Appel, B., Korzh, V., Glasgow...