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Keywords: Fat body
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Journal Articles
Journal: Development
Development (2022) 149 (6): dev200243.
Published: 23 March 2022
... crossing an HA Frankenbody fly with an HA-tagged POI fly. Strikingly, the GFP-mCherry tandem fluorescent-tagged HA Frankenbody revealed a block in autophagic flux and an accumulation of enlarged autolysosomes in the last instar larval and prepupal fat body. Mechanistically, lysosomal activity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (18): dev188813.
Published: 23 September 2020
...Zhongxia Wu; Qiongjie He; Baojuan Zeng; Haodan Zhou; Shutang Zhou ABSTRACT Vitellogenin (Vg) is a prerequisite for egg production and embryonic development after ovipositioning in oviparous animals. In many insects, juvenile hormone (JH) promotes fat body cell polyploidization for the massive Vg...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (6): dev158865.
Published: 14 March 2018
... is stored in two different forms: the disaccharide trehalose and the branched polymer glycogen. Glycogen is synthesized and stored in several tissues, including in muscle and the fat body. Despite the major role of the fat body as a center for energy metabolism, the importance of its glycogen content...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4104–4109.
Published: 1 November 2014
... that the fly fat body, which is functionally equivalent to the mammalian liver, also contributes to tracheal morphogenesis. Serp was expressed by the fat body, and the secreted Serp was taken up by the tracheal cells and translocated to the lumen to functionally support normal tracheal development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (12): 2015–2025.
Published: 15 June 2009
..., but its molecular mechanism remains conjectural. Here we report that genetic ablation of the corpus allatum cells of the Drosophila ring gland (the JH source) resulted in JH deficiency, pupal lethality and precocious and enhanced programmed cell death (PCD) of the larval fat body. In the fat body...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (14): 2605–2614.
Published: 15 July 2007
.... Drosophila CYLD is broadly expressed during development and, in adult animals, is localized in the fat body,ovaries, testes, digestive tract and specific areas of the nervous system. We demonstrate that the protein product of Drosophila CYLD (CYLD), like its mammalian counterpart, is a deubiquitylating...
Journal Articles
Journal: Development
Development (2004) 131 (10): 2317–2327.
Published: 15 May 2004
... of cell division. Hemizygous dm 4 /Y mutants arrest as second instar larvae, and fat body nuclei of dm 4 /Y mutants fail to attain normal size and normal levels of DNA, resulting from a reduced frequency of S-phase. Thus, dMyc is required for endoreplication and larval growth. In support of this, dMyc...
Journal Articles
Journal: Development
Development (2003) 130 (16): 3683–3689.
Published: 15 August 2003
...Marcella Marchetti; Laura Fanti; Maria Berloco; Sergio Pimpinelli We have analyzed the expression of homeotic Bithorax Complex proteins in the fat bodies of Drosophila larvae by staining with specific antibodies. We have found that these proteins are differentially expressed along...