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Zachary Steinberg, Christopher Myers, Vernon M. Heim, Colin A. Lathrop, Ivan T. Rebustini, Julian S. Stewart, Melinda Larsen, Matthew P. Hoffman
Development (2005) 132 (6): 1223–1234.
Published: 15 March 2005
... submandibular glands decreases when either FGFR2 expression is downregulated or soluble recombinant FGFR2b competes out the endogenous growth factors. However, a combination of neutralizing antibodies to FGF1, FGF7 and FGF10 is required to inhibit branching in the intact gland, suggesting that multiple FGF...
Includes: Multimedia, Supplementary data
Matthew P. Hoffman, Benjamin L. Kidder, Zachary L. Steinberg, Saba Lakhani, Susan Ho, Hynda K. Kleinman, Melinda Larsen
Development (2002) 129 (24): 5767–5778.
Published: 15 December 2002
... SU5402 treatment. FGFR1 signaling regulates Fgfr1, Fgf1, Fgf3 and Bmp7 expression and indirectly regulates Fgf7, Fgf10 and Bmp4 . Exogenous FGFs and BMPs added to glands in culture reveal distinct effects on gland morphology. Glands cultured with SU5402 were then rescued with exogenous BMP7, FGF7...
Includes: Supplementary data