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Keywords: FGF signalling
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (6): dev184143.
Published: 16 March 2020
... Marques , S. R. , Lee , Y. , Poss , K. D. and Yelon , D. ( 2008 ). Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart . Dev. Biol.   321 , 397 - 406 . 10.1016/j.ydbio.2008.06.033 McInnes , L. , Healy , J. , Saul , N...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (24): dev180620.
Published: 16 December 2019
... be expanded as an in vitro model for naïve extra-embryonic endoderm (nEnd). Consistent with observations made in mouse, human PrE differentiation is dependent on FGF signalling in vitro , and we show that, by inhibiting FGF receptor signalling, we can simplify naïve pluripotent culture conditions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (12): 2294–2305.
Published: 15 June 2017
.... , Ornitz , D. and Beebe , D. C. ( 2014 ). FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands . Development   141 , 2691 - 2701 . 10.1242/dev.108944 Gaete , M. , Fons , J. M. , Popa , E. M. , Chatzeli , L...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (13): 2443–2454.
Published: 1 July 2016
... of Tc-dof than Tc-htl ( Donitz et al., 2015 ; Schmitt-Engel et al., 2015 ). This indicates that Tc-dof is not required for all aspects of FGF signalling in Tribolium , which is in contrast to Drosophila where dof mutants almost completely abolish FGF signalling ( Imam et al., 1999 ; Vincent...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (12): 2184–2193.
Published: 15 June 2015
... by The Company of Biologists Ltd 2015 Summary: In the developing Drosophila eye, the TRF2 complex regulates downstream factors including Pdm3 and Cut to control glial proliferation and differentiation, respectively. Drosophila Glial proliferation Glial differentiation FGF signalling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (16): 3266–3276.
Published: 15 August 2014
... as the neural programme is established. We further demonstrate that transcription of one such gene, HDAC1 , is dependent on FGF signalling, making a novel link between signals that control neural differentiation and transcription of a core regulator of chromatin organisation. Our work implicates new signalling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1104–1109.
Published: 1 March 2014
... at position B-2 within the PSM. Heat-shock experiments, however, suggest that an earlier future somite boundary exists at B-5, but the molecular signature of this boundary remains unidentified. Here, we characterized fibroblast growth factor (FGF) signal activity within the PSM, and demonstrated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 372–384.
Published: 15 January 2013
... and gene knockdown and/or overexpression experiments, we demonstrate that Fgf signalling acts via another ETS-domain transcription factor, Etv5b (Erm), to induce hypothalamic 5-HT neurons. We provide evidence that Etv5b exerts its effects by regulating cell cycle parameters in 5-HT progenitors. Our results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 2978–2987.
Published: 15 August 2012
... boundary cells positions fgf20a neurons (red) in the segment centre. The cluster of fgf20a neurons creates a focussed source of FGF signals (red lines) that inhibit neurogenesis in the adjacent neural epithelium, restricting the neurogenic zones (green) to being adjacent to boundaries. ( C , D...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (10): 1761–1769.
Published: 15 May 2008
...Fabian Rentzsch; Jens H. Fritzenwanker; Corinna B. Scholz; Ulrich Technau Fibroblast growth factor (FGF) signalling regulates essential developmental processes in vertebrates and invertebrates, but its role during early metazoan evolution remains obscure. Here, we analyse the function of FGF...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (24): 5553–5564.
Published: 15 December 2005
... of Fgf signalling at distinct points of the MAPK signalling cascade in the neck lateral mesoderm and ectoderm. * Author for correspondence (e-mail: susanne.dietrich@kcl.ac.uk ) 5 10 2005 ©2005. 2005 To detect activated MAPK signalling, rapid fixation in 4% PFA was required...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (6): 1305–1314.
Published: 15 March 2005
... specification and differentiation. * Author for correspondence (e-mail: a.munsterberg@uea.ac.uk ) 14 1 2005 ©2005. 2005 FGF signalling Chick Somite Tendon Rib Mkp3 ERK MAP kinase Scleraxis During vertebrate embryogenesis, epithelial somites are generated sequentially...
Journal Articles
Journal: Development
Development (2004) 131 (21): 5277–5286.
Published: 1 November 2004
... to be responsible for the apoptotic signal/s of cavitation; the second, originating in the BM, was considered necessary for the maintenance and survival of the columnar ectoderm( Coucouvanis and Martin,1995 ). The work to be described here started as a study of the role of FGF signalling in EB differentiation...