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Keywords: Erythro-myeloid progenitors
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Journal Articles

Dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing

In collection:
Stem cells & regeneration
Jiayi Tu, Shanshan Yu, Jingzhen Li, Mengmeng Ren, Yangjun Zhang, Jiong Luo, Kui Sun, Yuexia Lv, Yunqiao Han, Yuwen Huang, Xiang Ren, Tao Jiang, Zhaohui Tang, Mark Thomas Shaw Williams, Qunwei Lu, Mugen Liu
Journal: Development
Development (2022) 149 (17): dev200450.
https://doi.org/10.1242/dev.200450
Published: 30 August 2022
...-related diseases. How splicing factor mutations perturb hematopoiesis, especially in the differentiation of erythro-myeloid progenitors (EMPs), remains elusive. Dhx38 is a pre-mRNA splicing-related DEAH box RNA helicase, for which the physiological functions and splicing mechanisms during hematopoiesis...
View article titled, Dhx38 is required for the maintenance and differentiation of <span class="search-highlight">erythro</span>-<span class="search-highlight">myeloid</span> <span class="search-highlight">progenitors</span> and hematopoietic stem cells by alternative splicing
Open the PDF for Dhx38 is required for the maintenance and differentiation of <span class="search-highlight">erythro</span>-<span class="search-highlight">myeloid</span> <span class="search-highlight">progenitors</span> and hematopoietic stem cells by alternative splicing in another window
Includes: Supplementary data
Journal Articles

Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placenta

In collection:
Reproductive biology
Laina Freyer, Yvan Lallemand, Pascal Dardenne, Alina Sommer, Anne Biton, Elisa Gomez Perdiguero
Journal: Development
Development (2022) 149 (8): dev200104.
https://doi.org/10.1242/dev.200104
Published: 22 April 2022
... pulse-labeling traced the ontogeny of HBCs from yolk sac-derived erythro-myeloid progenitors, with a minor contribution from fetal hematopoietic stem cells later on. Single-cell RNA-sequencing revealed transcriptional similarities between placenta macrophages and erythro-myeloid progenitor-derived fetal...
View article titled, <span class="search-highlight">Erythro</span>-<span class="search-highlight">myeloid</span> <span class="search-highlight">progenitor</span> origin of Hofbauer cells in the early mouse placenta
Open the PDF for <span class="search-highlight">Erythro</span>-<span class="search-highlight">myeloid</span> <span class="search-highlight">progenitor</span> origin of Hofbauer cells in the early mouse placenta in another window
Includes: Supplementary data