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Keywords: Epithelium
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Journal Articles
Journal: Development
Development (2021) 148 (20): dev199731.
Published: 14 October 2021
... flow reorients the axis of planar polarity in the wing epithelium of Drosophila . Cell 142 , 773 - 786 . 10.1016/j.cell.2010.07.042 Bai , J. , Chiu , W. , Wang , J. , Tzeng , T. , Perrimon , N. and Hsu , J. ( 2001 ). The cell adhesion molecule Echinoid defines...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (12): dev199542.
Published: 28 June 2021
... tissues ( Ehf −/− ) or specifically in the gut epithelium. Ehf −/− mice were born at the expected Mendelian ratio, but showed reduced body weight gain, and developed a series of pathologies requiring most Ehf −/− mice to reach an ethical endpoint before reaching 1 year of age. These included papillomas...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (10): dev192054.
Published: 25 May 2021
... transcription factors as upstream regulators of Wnt5a in the 4V ChP epithelium. Neuron Nadační Fond Na Podporu Vědy 23/2016 The choroid plexus (ChP) is a sheet of predominantly epithelial cells that produces cerebrospinal fluid (CSF), secretes factors important for brain development and forms...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev198036.
Published: 20 April 2021
... markers associated with EMT. EMT MET Cancer metastasis Developmental models Epithelium Mesenchyme Epithelial-mesenchymal transition (EMT) and its reverse process mesenchymal-epithelial transition (MET) are dynamic processes – collectively referred to as EMTs – that are associated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev196030.
Published: 15 February 2021
... of the head. In the eye and ear, these neural crest cells then transform back into an epithelium, via mesenchymal-to-epithelial transition (MET), highlighting the flexibility of this population. Elsewhere in the head, the epithelium loses its integrity and transforms into mesenchyme. Here, we review...
Journal Articles
Journal: Development
Development (2020) 147 (4): dev181560.
Published: 20 February 2020
... or Lamp3 + /Sox9 + cells were quantified using the ‘colocalize spots’ function in the Imaris XT analysis package. Images used in these quantifications encompass at least five random views of distal epithelium from at least three embryos per genotype and treatment condition. Images were captured to avoid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (20): dev175133.
Published: 2 October 2019
.... Summary: Reduction of the adherens junction component β-catenin is a crucial mechanism for regulating the cell-cell interactions that ensure rapid epidermal wound closure in Drosophila larvae. Wound repair Adherens junctions Epithelium Casein kinase 1α β-Catenin Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev165399.
Published: 1 August 2018
... and regeneration, and highlight how these diverse inputs influence stem cell plasticity. The turnover dynamics of the multilayered, stratified skin epithelium, the epidermis, are very similar to those of the intestinal epithelium, fully renewing every 7-10 days ( Potten et al., 1987 ). Epidermal stem cells...
Journal Articles
Journal: Development
Development (2018) 145 (8): dev155325.
Published: 24 April 2018
...‴) embryo. Dashed lines highlight the boundaries; the asterisks mark cells that delaminate from the epithelium; arrows indicate cells undergoing intercalation; arrowheads indicate cells undergoing intercalation events associated with cell divisions. Anterior is left and ventral is up. Scale bars: 10 µm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 708–719.
Published: 15 February 2017
... the equator. To elucidate the mechanisms underlying lens epithelial cell movement, we conducted time-lapse imaging of zebrafish lens epithelium. Lens epithelial cells do not intermingle but maintain their relative positions during development. Cell division induces epithelial rearrangement, which subsequently...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (1): 151–162.
Published: 1 January 2017
...Katsumi Fumoto; Hisako Takigawa-Imamura; Kenta Sumiyama; Tomoyuki Kaneiwa; Akira Kikuchi In lung development, the apically constricted columnar epithelium forms numerous buds during the pseudoglandular stage. Subsequently, these epithelial cells change shape into the flat or cuboidal pneumocytes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2160–2171.
Published: 15 June 2016
... by severe ciliopathies, such as Meckel syndrome, present several ocular surface disease conditions of unclear pathogenesis. Here, we show that primary cilia are predominantly present on basal cells of the mouse corneal epithelium (CE) throughout development and in the adult. Conditional ablation of cilia...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (11): 1958–1970.
Published: 1 June 2016
... proteins for the development of a 3D, cyst-like or follicular structure. The impaired follicle formation observed in the absence of Smad1 and Smad5 is reminiscent of the defect observed in the absence of endothelial cells upon Vegfa inactivation in thyroid epithelium ( Hick et al., 2013 ). Although...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1388–1399.
Published: 15 April 2016
... in epithelia. We have studied the role of spectrins during epithelia morphogenesis using the Drosophila follicular epithelium (FE). As previously described, we show that α-Spectrin and β-Spectrin are essential to maintain a monolayered FE, but, contrary to previous work, spectrins are not required to control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (2): 264–275.
Published: 15 January 2016
.... Inductive interactions between epithelium and mesenchyme regulate gut development, but the influence of these interactions on ENS development is unknown. Epithelial-mesenchymal recombinations were constructed using avian hindgut mesenchyme and non-intestinal epithelium from the bursa of Fabricius...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (1): 101–112.
Published: 1 January 2016
... understood. The embryonic pancreas, which gives rise to β-cells, undergoes early epithelial rearrangements, including transient stratification of an initially monolayered epithelium, followed by microlumen formation and later resolution into branches. Within the epithelium, a multipotent progenitor cell (MPC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3954–3963.
Published: 15 November 2015
..., root-forming cervical loops and enamel-forming ameloblasts. Enamel knots are signaling centers that define the positions of cusp tips in a tooth by instructing the adjacent epithelium to fold and proliferate. Here, we show that the forkhead-box transcription factor Foxi3 inhibits formation of enamel...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (20): 4006–4017.
Published: 15 October 2014
...), which is enriched at adherens junctions ( Fig. 4 ) ( Muller and Wieschaus, 1996 ). From this, we inferred the position along the apico-basal axis of all membranous/cortical lines with comparable localisations ( supplementary material Table S4 ). The epithelium of stage 5-10 embryos is still polarizing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4740–4750.
Published: 1 December 2013
... epithelium is a landmark-rich tissue, marked by regularly spaced ridges (rugae), making it an excellent model in which to analyse the contributions of cellular processes to directional tissue growth. We captured confocal stacks of entire fixed mouse palate epithelia throughout the mid-gestation growth period...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (9): 2015–2026.
Published: 1 May 2013
... molecular evidence that the human thymic epithelium derives solely from the third pharyngeal pouch, as in the mouse, in contrast to previous suggestions. Finally, we define the timing of onset of hematopoietic cell colonization and epithelial cell differentiation in the human thymic primordium, showing...
Includes: Supplementary data