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Keywords: Epithelial polarity
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Journal Articles
Journal: Development
Development dev.200110.
Published: 10 January 2022
... 2022 http://www.biologists.com/user-licence-1-1/ Notch signaling Drosophila Epithelial polarity Neoplasia Agence Nationale de la Recherche https://dx.doi.org/10.13039/501100001665 ANR-18-CE14-0041 Ligue Contre le Cancer Fondation ARC pour la Recherche...
Journal Articles
Journal: Development
Development (2021) 148 (19): dev199513.
Published: 05 October 2021
... the spatial restriction of the activin response in the context of the polarized epithelium. Huntington's disease Human embryonic stem cells 2D gastruloids TGFβ signaling Epithelial polarity CHDI Foundation http://dx.doi.org/10.13039/100005725 A-9423 Despite the fact that HD has...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (15): dev175497.
Published: 12 August 2019
... confers apical identity, Par-complex assembly and Crb accumulation to promote epithelial morphogenesis. Epithelial polarity Cdc42 Par6 Par3 Bazooka aPKC Crumbs Par complex Epithelial cell polarity and morphogenesis involve the specification and maturation of distinct plasma membrane...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157909.
Published: 26 January 2018
... by the basolateral PDZ protein Scribble . Nature   403 , 676 - 680 . 10.1038/35001108 Bilder , D. , Schober , M. and Perrimon , N. ( 2003 ). Integrated activity of PDZ protein complexes regulates epithelial polarity . Nat. Cell Biol.   5 , 53 - 58 . 10.1038/ncb897 Bischof , J...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1684–1694.
Published: 01 May 2015
.... ( 2012 ). An association between type Igamma PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization . Mol. Biol. Cell   23 , 87 - 98 . 10.1091/mbc.E11-05-0449 Yochem , J. , Tuck , S. , Greenwald , I. and Han , M. ( 1999 ). A gp330/megalin-related...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1305–1314.
Published: 01 April 2015
...Joaquim Grego-Bessa; Jeffrey Hildebrand; Kathryn V. Anderson The genetic control of mammalian epithelial polarity and dynamics can be studied in vivo at cellular resolution during morphogenesis of the mouse neural tube. The mouse neural plate is a simple epithelium that is transformed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (13): 2787–2797.
Published: 01 July 2013
... by neighboring wild-type cells. In larger clones, these signals are lacking because of abutting mutant cells, leading to a mutant phenotype. Thus, our findings underscore the importance of cell signaling for epithelial polarity. The genotype of RPE cells is not decisive for the phenotype of abutting RPCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (11): 2061–2070.
Published: 01 June 2012
... adaptor AP-1 in the C. elegans intestine, we found that AP-1 is required for epithelial polarity maintenance. Depletion of AP-1 subunits does not affect epithelial polarity establishment or the formation of the intestinal lumen. However, the loss of AP-1 affects the polarised distribution of both apical...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (11): 2050–2060.
Published: 01 June 2012
... polarize around a central lumen, provides a simple system with which to understand the coordination of epithelial polarity. We show that cell fate regulators cause pharyngeal precursor cells to group into a bilaterally symmetric, rectangular array of cells called the double plate. The double plate cells...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (9): 2057–2067.
Published: 01 May 2005
... (e-mail: sive@wi.mit.edu ) 15 2 2005 ©2005. 2005 Brain ventricle formation Brain structure Circulation Morphogenesis Zebrafish Lumen inflation snakehead ( snk ) nagie oko ( nok ) Neural tube Epithelial polarity MAGUK family Na + K + ATPase atp1a1a.1...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 977–986.
Published: 01 March 2005
... and inhibit apical membrane identity. The balance between these two antagonistic activities acts to establish and maintain apical and basal lateral membrane domains during early vertebrate development. Similar interactions have been reported in the establishment of embryonic epithelial polarity in Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 1939–1948.
Published: 01 May 2004
... pathway. Clones for null alleles of Pvr or expression of RNAi constructs showed no phenotypes in the wing disc or pupal wing, suggesting that Pvr plays a redundant role in this tissue. However, when uniform expression of a constitutively dimerizing receptor was induced, loss of epithelial polarity...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2657–2668.
Published: 15 June 2003
... )]. The apical localisation of aPKC was found to be present in isolated blastomeres( Fig. 8A ) and so does not require cell contact. This is consistent with previous results showing that isolated blastomeres maintain epithelial polarity( Muller and Hausen, 1995 ; Cardellini et al., 1996 ; Fesenko et al., 2000...
Includes: Multimedia, Supplementary data