... spermatid injection H3K27me3 Epigenetic inheritance Spermiogenesis Highlighted Article: Histone turnover-mediated reduction of H3K27me3 during spermiogenesis is important for chromatin accessibility in early mouse embryos. © 2022. Published by The Company of Biologists Ltd 2022 26...

... does not determine the rate of pluripotency exit. FRET ERK Single cell Stem cells Nanog Epigenetic inheritance Mouse embryonic stem cells (ESCs) are derived from the inner cell mass of blastocysts, and can give rise to all cells of the developing embryo ( Evans and Kaufman, 1981...

... in the transgenerational epigenetic landscape of T2DM . Nat. Rev. Endocrinol.   12 , 441 - 451 . 10.1038/nrendo.2016.87 Bohacek , J. and Mansuy , I. M. ( 2017 ). A guide to designing germline-dependent epigenetic inheritance experiments in mammals . Nat. Methods   14 , 243 - 249 . 10.1038/nmeth...

...Julie Zhouli Ni; Natallia Kalinava; Sofia Galindo Mendoza; Sam Guoping Gu ABSTRACT Nuclear RNA interference provides a unique approach to the study of RNA-mediated transgenerational epigenetic inheritance. A paradox in the field is that expression of target loci is necessary for the initiation...

... that in our system it is the timing and location but not the other parameters that are the decisive factors of epigenetic inheritance. Our data reveal the extraordinary malleability of the fetal epigenome and the existence of a novel type of locus supporting transgenerational epigenetic inheritance...

... that enhancer-ME communication mediates repression and epigenetic inheritance of gene expression ( Muller and Kassis, 2006 ) and that MEs are interchangeable modules ( Americo et al., 2002 ; Chiang et al., 1995 ; Kozma et al., 2008 ). It is interesting to note in this context that enhancer-PRE communication...