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Keywords: Endoderm
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Journal Articles
Journal: Development
Development (2023) 150 (22): dev202010.
Published: 16 November 2023
... a two-dimensional chemo-mechanical model to investigate how mechanical properties of the endoderm and transport properties of fibroblast growth factor (FGF) regulate avian hindgut morphogenesis in a coordinated manner. Posterior endoderm cells convert a gradient of FGF ligands into a contractile force...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (10): dev201023.
Published: 16 May 2023
...Benoit Haerlingen; Robert Opitz; Isabelle Vandernoot; Angelo Molinaro; Meghna Parakkal Shankar; Pierre Gillotay; Achim Trubiroha; Sabine Costagliola ABSTRACT Thyroid tissue, the site of de novo thyroid hormone biosynthesis, is derived from ventral pharyngeal endoderm and defects in morphogenesis...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (17): dev199771.
Published: 3 September 2021
... approaches. Abrogation of zygotic Klf expression during M. leidyi embryogenesis resulted in abnormal development of several organs, including the pharynx, tentacle bulbs and apical organ. Our data suggest an ancient role for Klf genes in regulating endodermal patterning, possibly through regulation of cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194738.
Published: 23 December 2020
...Kazunori Okada; Shinji Takada ABSTRACT Pharyngeal arches (PAs) are segmented by endodermal outpocketings called pharyngeal pouches (PPs). Anterior and posterior PAs appear to be generated by different mechanisms, but it is unclear how the anterior and posterior PAs combine. Here, we addressed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev185108.
Published: 12 April 2020
... novel dorsal and ventral hindgut domains, and show that ventrolateral hindgut cells populate the majority of the colonic epithelium. A Wnt3a-β-catenin-Sp5/8 pathway, which is active in the dorsal hindgut endoderm, is required for hindgut extension and colon formation. Interestingly, the absence of Wnt...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (11): dev150920.
Published: 3 June 2019
...Sonja Nowotschin; Anna-Katerina Hadjantonakis; Kyra Campbell ABSTRACT The endoderm is a progenitor tissue that, in humans, gives rise to the majority of internal organs. Over the past few decades, genetic studies have identified many of the upstream signals specifying endoderm identity in different...
Journal Articles
Journal: Development
Development (2019) 146 (2): dev167965.
Published: 22 January 2019
... morphogenetic protein 4 (BMP4) emanating from the pharyngeal endoderm are important in instructing region-specific NCC condensation to form malleus-incus and stapes, respectively, in mouse. Tissue-specific knockout of Shh in the pharyngeal endoderm or Smo (a transducer of SHH signaling) in NCCs causes the loss...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev163535.
Published: 14 September 2018
...Zairan Liu; Stephanie Woo; Orion D. Weiner ABSTRACT During gastrulation, endodermal cells actively migrate to the interior of the embryo, but the signals that initiate and coordinate this migration are poorly understood. By transplanting ectopically induced endodermal cells far from the normal...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Human development
Journal: Development
Development (2018) 145 (17): dev163550.
Published: 16 August 2018
...N. Ray Dunn; Brigid L. M. Hogan ABSTRACT The historic town of Taos, New Mexico, with its rich multicultural history of art and craft, was the site of the second Keystone Symposium on ‘Endoderm Development and Disease’, which was held in February 2018. The theme of the meeting was ‘Cross-Organ...
Journal Articles
Journal: Development
Development (2018) 145 (1): dev154393.
Published: 11 January 2018
...Abigail S. Tucker; Carlene J. Dyer; Juan M. Fons Romero; Tathyane H. N. Teshima; Jennifer C. Fuchs; Hannah Thompson ABSTRACT The middle ear epithelium is derived from neural crest and endoderm, which line distinct regions of the middle ear cavity. Here, we investigate the distribution of putative...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (12): 2123–2140.
Published: 15 June 2017
... organogenesis, highlighting the factors involved in thyroid progenitor specification and the events occurring during thyroid gland morphogenesis. Thyroid Endoderm Pharyngeal Neural crest Evolution Morphogenesis The thyroid gland ( Fig. 1 ) and its hormones play multifaceted roles in organ...
Journal Articles
Journal: Development
Development (2017) 144 (9): 1629–1634.
Published: 1 May 2017
... coordinated expression in the pharyngeal endoderm, tissue-specific roles of these factors for establishing the regional identities within this tissue have not been demonstrated. Here, we show that Hox1 is essential for the establishment of AP axial identity of the endostyle, a major structure...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1283–1295.
Published: 1 April 2017
...Mariana L. Stevens; Praneet Chaturvedi; Scott A. Rankin; Melissa Macdonald; Sajjeev Jagannathan; Masashi Yukawa; Artem Barski; Aaron M. Zorn Digestive system development is orchestrated by combinatorial signaling interactions between endoderm and mesoderm, but how these signals are interpreted...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 281–291.
Published: 15 January 2017
... contacts and creates directionally biased geometry. Here, we demonstrate that FN is deposited as pillars between widely separated germ layers, namely the somitic mesoderm and the endoderm, in quail embryos. Alongside the FN pillars, long filopodia protrude from the basal surfaces of somite epithelial cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 345–355.
Published: 15 January 2017
... validate several strategies to spatially restrict illumination and thus gene induction with our new TAEL (TA4-EL222) system. As a functional example, we show that TAEL is able to induce ectopic endodermal cells in the presumptive ectoderm via targeted sox32 induction. We also demonstrate that TAEL can...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (21): 4027–4037.
Published: 1 November 2016
...Virginia E. Bain; Julie Gordon; John D. O'Neil; Isaias Ramos; Ellen R. Richie; Nancy R. Manley The thymus and parathyroids develop from third pharyngeal pouch (3rd pp) endoderm. Our previous studies show that S hh null mice have smaller, aparathyroid primordia in which thymus fate specification...
Includes: Supplementary data