1-10 of 10
Keywords: Endochondral ossification
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2017) 144 (21): 4026–4036.
Published: 1 November 2017
... activity causes craniosynostosis. Constitutive activation of PDGFRα leads to expansion of cartilage underlying the coronal sutures, which contribute to suture closure through endochondral ossification, in a process regulated in part by PI3K/AKT signaling. Our results thus identify a novel mechanism...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (19): 3533–3546.
Published: 1 October 2017
... ossification Glucose metabolism Endochondral ossification is an essential process for long bone growth, for which a cartilage template is used. Here, chondrocytes undergo proliferation and hypertrophic differentiation (i.e. maturation), forming a distinctive growth plate that drives longitudinal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 221–234.
Published: 15 January 2017
...Diane P. Hu; Federico Ferro; Frank Yang; Aaron J. Taylor; Wenhan Chang; Theodore Miclau; Ralph S. Marcucio; Chelsea S. Bahney ABSTRACT Fractures heal predominantly through the process of endochondral ossification. The classic model of endochondral ossification holds that chondrocytes mature...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (4): 648–657.
Published: 15 February 2016
...Stephen Tonna; Ingrid J. Poulton; Farzin Taykar; Patricia W. M. Ho; Brett Tonkin; Blessing Crimeen-Irwin; Liliana Tatarczuch; Narelle E. McGregor; Eleanor J. Mackie; T. John Martin; Natalie A. Sims The majority of the skeleton arises by endochondral ossification, whereby cartilaginous templates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (7): 1433–1444.
Published: 1 April 2011
... for correspondence ( mikenaski@yahoo.com ) Competing interests statement The authors declare no competing financial interests. 6 1 2011 © 2011. 2011 Endochondral ossification Pten Perichondrium FGF18 Dermo1 cre Osteoprogenitors Mouse Endochondral ossification...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (4): 551–559.
Published: 15 February 2010
... the formation of a mammalian digit blastema. Unlike the endogenous regeneration response that involves redifferentiation by direct ossification (evolved regeneration), the BMP-induced response involves endochondral ossification (redevelopment). Our evidence suggests that BMP treatment triggers a reprogramming...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (24): 4143–4153.
Published: 15 December 2009
... leads to severe skeletal defects, including delayed ossification and low bone mass, short stature and short limbs. Atf4 is expressed in proliferative and prehypertrophic growth plate chondrocytes, suggesting an autonomous function of Atf4 in chondrocytes during endochondral ossification. In Atf4...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (17): 4123–4133.
Published: 1 September 2003
... Matrix metalloproteinase 9 Vascular endothelial growth factor Endochondral ossification Cartilage Bone healing Mechanical environment Mouse The bony skeleton possesses an astounding regenerative potential. Unlike other adult tissues, which generate scar tissue at the site of an injury...
Journal Articles
Journal: Development
Development (2002) 129 (16): 3783–3793.
Published: 15 August 2002
... in mature osteocytes during mineralization. *Author for correspondence (e-mail: peter.lonai@weizmann.ac.il ) 17 5 2002 © 2002. 2002 Transcriptional alternatives FGF Endochondral ossification Craniosynostosis Gene targeting Mouse Three of the four fibroblast growth...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4523–4534.
Published: 15 November 2001
...Eleonora Minina; Hans Markus Wenzel; Conny Kreschel; Seth Karp; William Gaffield; Andrew P. McMahon; Andrea Vortkamp During endochondral ossification, two secreted signals, Indian hedgehog (Ihh) and parathyroid hormone-related protein (PTHrP), have been shown to form a negative feedback loop...