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Keywords: Emx2
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Journal Articles
Journal: Development
Development (2017) 144 (16): 2994–3005.
Published: 15 August 2017
... further reveals clusters of co-regulated genes, with in situ hybridization confirming the domain-specific expression of novel genes. We then created loss-of-function alleles for 12 genes and uncovered antagonistic functions of two new Edn1 targets, follistatin a ( fsta ) and emx2 , in regulating...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (17): 3177–3190.
Published: 1 September 2007
..., cyclin D1 (Ccnd1) and Emx2. This is associated with anti-apoptotic and proliferative effects in epithelial progenitors, whereas cells with impaired TCF/Lef-dependent transcription are progressively depleted from the epithelial lineage. In vivo,TCF/Lef-responsive genes comprise a conserved transcriptional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (7): 1219–1229.
Published: 1 April 2006
... pathway. In addition,loss of β-catenin results in a severe agenesis of the scapula. Concurrently, the expression of two genes, Pax1 and Emx2 ,which have been implicated in scapula development, is lost in β-catenin loss-of-function limbs; however, only Emx2 is upregulated in gain-of-function limbs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (8): 1785–1793.
Published: 15 April 2005
..., neurons located at the ventral midbrain-forebrain border (MFB) give rise to the medial longitudinal fascicle(mlf) and the posterior commissure (pc). We demonstrate that the homeobox genes Sax1, Six3, Emx2 and Pax6 are expressed in distinct domains in this area, suggesting that the specification of mlf...
Journal Articles
Journal: Development
Development (2004) 131 (14): 3307–3317.
Published: 15 July 2004
... to maintain anterior neuroectoderm once induced. Furthermore, Otx2 under the AN enhancer cooperates with Emx2 in diencephalon development. The AN enhancer region is conserved among mouse, human and Xenopus ; moreover, the counterpart region in Xenopus exhibited an enhancer activity in mouse anterior...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4919–4929.
Published: 15 October 2003
.... During neurulation, loss of GPC4 disrupts expression of dorsal forebrain genes, such as Emx2 , whereas genes marking the ventral forebrain and posterior central nervous system continue to be expressed. This loss of GPC4 activity also causes apoptosis of forebrain progenitors during neural tube closure...
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (24): 5779–5788.
Published: 15 December 2002
... fates. * Author for correspondence (e-mail: cliff@drugs.bsd.uchicago.edu ) 12 9 2002 ©2002. 2002 Bain nuclei Oculomotor neurons Red nucleus Homeobox genes Emx2 Sonic hedgehog FGF8 Isthmus Chick Mouse In the adult brain, many neurons are organized into well...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (9): 1653–1664.
Published: 1 May 1997
...Norimasa Miyamoto; Michio Yoshida; Shigeru Kuratani; Isao Matsuo; Shinichi Aizawa ABSTRACT The homeobox gene Emx2 is a mouse homologue of a Drosophila head gap gene empty spiracles ( ems ) and is essential for the development of dorsal telencephalon ( Yoshida, M., Suda, Y., Matsuo, I., Miyamoto, N...
Journal Articles
Journal: Development
Development (1997) 124 (1): 101–111.
Published: 1 January 1997
...Michio Yoshida; Yoko Suda; Isao Matsuo; Norimasa Miyamoto; Naoki Takeda; Shigeru Kuratani; Shinichi Aizawa ABSTRACT The genes Emx1 and Emx2 are mouse cognates of a Drosophila head gap gene, empty spiracles , and their expression patterns have suggested their involvement in regional patterning...
Journal Articles
Journal: Development
Development (1996) 122 (12): 3893–3898.
Published: 1 December 1996
...M. Pellegrini; A. Mansouri; A. Simeone; E. Boncinelli; P. Gruss ABSTRACT Emx 1 and 2 are the murine homologues of the Drosophila empty spiracles gene and based on their expression pattern may be involved in the regional specification of the mammalian forebrain. During early embryogenesis, Emx2...