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Keywords: Embryo cultureClose
Patricia Ybot-Gonzalez, Dawn Savery, Dianne Gerrelli, Massimo Signore, Claire E. Mitchell, Clare H. Faux, Nicholas D. E. Greene, Andrew J. Copp
Development (2007) 134 (4): 789–799.
Published: 15 February 2007
... plate, consistent with a cell-autonomous disturbance of convergent extension. Inhibitor studies in whole-embryo culture demonstrated a requirement for signalling via RhoA-Rho kinase, but not jun N-terminal kinase, in convergent extension and the onset of neural tube closure. These findings identify...
Includes: Supplementary data
Development (2004) 131 (14): 3367–3379.
Published: 15 July 2004
... the neural tube to the developing heart. A cardiac neural crest lineage is also known to exist in mammals, although detailed information on its axial level of origin and migratory pattern are lacking. We used focal cell labelling and orthotopic grafting, followed by whole embryo culture, to determine...
Development (2004) 131 (5): 1157–1164.
Published: 1 March 2004
.... Curr. Biol. 9 , 946 -954. Jones, E. A., Crotty, D., Kulesa, P. M., Waters, C. W., Baron,M. H., Fraser, S. E. and Dickinson, M. E. ( 2002 ). Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture. Genesis 34 , 228 -235. Kimura, C., Yoshinaga, K., Tian, E...
Includes: Multimedia, Supplementary data
Development (2002) 129 (10): 2507–2517.
Published: 15 May 2002
... to be regulated by another notochordal factor. Attachment of surface ectoderm cells to the neural plate is required for dorsolateral bending, which ensures neural tube closure in the absence of sonic hedgehog signaling. Neurulation Neural plate Morphogenesis Embryo culture Notochord patched...
Development (2001) 128 (11): 2031–2038.
Published: 1 June 2001
... phenotype is strikingly different from that of embryos lacking RARα and RARβ (Aα/Aβmutants), in which we have previously shown that the territory corresponding to R5 and R6 is markedly enlarged. Administration of a pan-RAR antagonist at E8.0 to wild-type embryos cultured in vitro results in an Aα/Aβ-like...
Development (1986) 98 (1): 21–58.
Published: 1 November 1986
... orthotopically into host embryos of the same developmental stage except for area 1 (forebrain) grafts which were, for technical reasons, injected into area 2. After various periods of time in whole embryo culture, the embryos were examined by immunohistochemical staining in order to determine the new positions...
Development (1985) 86 (1): 271–281.
Published: 1 April 1985
... the uptake of protein by yolk sac (Freeman, Brent & Lloyd, 1982; Freeman & Lloyd, 1985) while two other teratogens, leupeptin and sodium aurothiomalate, were demonstrated to inhibit intralysosomal proteolysis in yolk sac (Freeman & Lloyd, 19836; Freeman Key words: Rat embryo; embryo culture; cathepsins...