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Keywords: ES cells
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Journal Articles
Journal: Development
Development (2017) 144 (7): 1221–1234.
Published: 1 April 2017
...Tüzer Kalkan; Nelly Olova; Mila Roode; Carla Mulas; Heather J. Lee; Isabelle Nett; Hendrik Marks; Rachael Walker; Hendrik G. Stunnenberg; Kathryn S. Lilley; Jennifer Nichols; Wolf Reik; Paul Bertone; Austin Smith Mouse embryonic stem (ES) cells are locked into self-renewal by shielding from...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (17): 3074–3084.
Published: 1 September 2016
... complex, and are dispensable for the maintenance of pluripotency. Sall4 NuRD ES cells Enhancer Transcription factor Co-repressor Embryonic stem cells (ESCs) have the potential to form any somatic cell type in the adult organism; that is, they are pluripotent. In order to properly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2024–2034.
Published: 15 May 2014
...: Department of Biology, University of Alabama at Birmingham, AL 35294, USA. ¶ Author for correspondence ( stor@uchicago.edu ) Ssm1 KRAB-zinc finger genes DNA methylation Gene inactivation ES cells Mouse development The role of epigenetic modification in the control of gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1423–1426.
Published: 1 April 2014
....2013.12.008 . Li M. A. , Pettitt S. J. , Yusa K. , Bradley A. ( 2010 ). Genome-wide forward genetic screens in mouse ES cells . Methods Enzymol. 477 , 217 – 242 . Li W. , Shuai L. , Wan H. , Dong M. , Wang M. , Sang L. , Feng C. , Luo...
Journal Articles
Journal: Development
Development (2013) 140 (13): 2828–2834.
Published: 1 July 2013
... The authors declare no competing financial interests. 7 5 2013 © 2013. Published by The Company of Biologists Ltd 2013 Long non-coding RNAs Ribosome profiling Embryogenesis Zebrafish ES cells Long non-coding RNAs (lncRNAs) have emerged as important regulators of gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (8): 1513–1524.
Published: 15 April 2008
... distinct multimeric protein complexes, the Polycomb repressive complexes 1 (PRC1) and 2(PRC2). Although PRC2 has been shown to share target genes with the core transcription network, including Oct3/4, to maintain embryonic stem (ES)cells, it is still unclear whether PcG proteins and the core transcription...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 3041–3048.
Published: 15 August 2007
... of the hemangioblast, an embryonic progenitor of the hematopoietic and endothelial lineages. Eng -/- , Eng +/- and Eng +/+ mouse embryonic stem (ES) cells were differentiated as embryoid bodies (EBs) and assayed for blast colony-forming cells (BL-CFCs). Our results showed a profound reduction in hemangioblast...
Journal Articles
Journal: Development
Development (2007) 134 (6): 1123–1132.
Published: 15 March 2007
...Keisuke Kaji; Jennifer Nichols; Brian Hendrich Mbd3 is a core component of the NuRD (Nucleosome Remodeling and Histone Deacetylation) co-repressor complex, and NuRD-mediated silencing has been implicated in cell fate decisions in a number of contexts. Mbd3-deficient embryonic stem (ES) cells made...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 885–896.
Published: 1 March 2005
...Peter Cartwright; Cameron McLean; Allan Sheppard; Duane Rivett; Karen Jones; Stephen Dalton Murine ES cells can be maintained as a pluripotent, self-renewing population by LIF/STAT3-dependent signaling. The downstream effectors of this pathway have not been previously defined. In this report, we...
Journal Articles
Journal: Development
Development (2004) 131 (21): 5277–5286.
Published: 1 November 2004
...Li Li; Esther Arman; Peter Ekblom; David Edgar; Patricia Murray; Peter Lonai This study investigates the establishment of alternative cell fates during embryoid body differentiation when ES cells diverge into two epithelia simulating the pre-gastrulation endoderm and ectoderm. We report...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1869–1879.
Published: 15 April 2004
... in murine embryos and embryonic stem (ES)cells, there have been few in vitro studies of these processes in primates. In this study, we investigated hematopoietic differentiation from cynomolgus monkey ES cells grown on OP9, a stromal cell line deficient in macrophage colony-stimulating factor. Primitive...
Journal Articles
Journal: Development
Development (2003) 130 (26): 6545–6553.
Published: 29 December 2003
...Julia Béjar; Yunhan Hong; Manfred Schartl Embryonic stem (ES) cell lines have provided very useful models to analyse differentiation processes. We present here the development of a differentiation system using ES-like cell lines from medaka. These cells were transfected with the melanocyte...
Journal Articles
Journal: Development
Development (2003) 130 (22): 5533–5541.
Published: 15 November 2003
...Björn Scheffler; Tanja Schmandt; Wolfgang Schröder; Barbara Steinfarz; Leila Husseini; Jörg Wellmer; Gerald Seifert; Khalad Karram; Heinz Beck; Ingmar Blümcke; Otmar D. Wiestler; Christian Steinhäuser; Oliver Brüstle Embryonic stem (ES) cells provide attractive prospects for neural...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (11): 2505–2512.
Published: 1 June 2003
...Koji Shimozaki; Kinichi Nakashima; Hitoshi Niwa; Tetsuya Taga Oct3/4 plays a critical role in maintaining embryonic stem cell pluripotency. Regulatable transgene-mediated sustained Oct3/4 expression in ES cells cultured in serum-free LIF-deficient medium caused accelerated differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (1985) 87 (1): 27–45.
Published: 1 June 1985
... Blastocyst-derived embryonic stem (ES) cells are established in vitro from substrate-attached blastocysts without passage of the cells through tumours. They are maintained in an undifferentiated pluripotent state by culturing on an embryonic fibroblast feeder layer and spontaneously -differentiate...