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Keywords: ECM
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Journal Articles
Journal: Development
Development (2021) 148 (9): dev197525.
Published: 10 May 2021
... reveals epithelia-to-mesenchyme transition (EMT) heterogeneity on the surface of developing mouse hearts. Proteoglycan again regulates epicardial EMT through dystroglycan localising within the Golgi apparatus. Epicardium EMT ECM Agrin Dystroglycan Golgi apparatus WT1 Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev184234.
Published: 17 July 2020
... migration, cells undergo cycles of coordinated attachment and detachment from the extracellular matrix (ECM). Embryonic migration processes that require cell-ECM attachment are dependent on the integrin family of adhesion receptors. Precise regulation of integrin-mediated adhesion is important for many...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (5): dev182303.
Published: 11 March 2020
... factors and impaired ECM remodeling/protease function. Estrogen receptor alpha Membrane initiated signaling Mammary gland Stem cells Paracrine signals ECM Estrogens, particularly 17β-estradiol (E2), are sex hormones that are widely implicated in mammary gland development, which occurs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev168948.
Published: 16 January 2019
...Georg Wolfstetter; Ina Dahlitz; Kathrin Pfeifer; Uwe Töpfer; Joscha Arne Alt; Daniel Christoph Pfeifer; Reinhard Lakes-Harlan; Stefan Baumgartner; Ruth H. Palmer; Anne Holz ABSTRACT Basement membranes (BMs) are specialized layers of extracellular matrix (ECM) mainly composed of Laminin, type IV...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (3): 475–485.
Published: 1 February 2011
...Lindsay Marjoram; Christopher Wright The spatiotemporally dynamic distribution of instructive ligands within embryonic tissue, and their feedback antagonists, including inherent stabilities and rates of clearance, are affected by interactions with cell surfaces or extracellular matrix (ECM). Nodal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (20): 3723–3732.
Published: 15 October 2007
... of different promoters, LTBP1 exists in two major forms, long (L) and short (S), each expressed in a temporally and spatially unique fashion. Both LTBP1 molecules covalently interact with latent TGF-β and regulate its function,presumably via interaction with the extracellular matrix (ECM). To explore...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 2913–2923.
Published: 15 August 2007
... because this is an important event required for cells to adhere to and migrate on ECM substrates( Parsons, 2003 ). We found that phosphorylation on tyrosine 861 (pY861) is the predominant form in ECs in the wild-type neonatal retinas and aortic rings (see Fig. S8A,B,I,J in the supplementary material...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (4): 631–640.
Published: 15 February 2006
... with an altered macromolecular composition of the ECM structuring the cells' migratory pathways. The presented results, extend our knowledge on Has2 function and, for the first time, demonstrate a developmental role for CD44 in vertebrates. On the whole, these data underlie and confirm the emerging importance...
Journal Articles
Journal: Development
Development (2003) 130 (1): 173–184.
Published: 1 January 2003
... of muscular dystrophy. Dystroglycan is a receptor for multiple extracellular matrix (ECM) molecules such as Laminin, agrin and perlecan, and plays a role in linking the ECM to the actin cytoskeleton;however, how these interactions are regulated and their basic cellular functions are poorly understood. Using...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1521–1532.
Published: 15 March 2002
...Hiroshi Shimizu; Xiaoming Zhang; Jinsong Zhang; Alexey Leontovich; Kaiyin Fei; Li Yan; Michael P. Sarras, Jr. As a member of the phylum Cnidaria, the body wall of hydra is organized as an epithelium bilayer (ectoderm and endoderm) with an intervening extracellular matrix (ECM). Previous studies...