... germline stem cells in the ovarian niche reveals their asymmetric division and centrosome behaviour, whereas tumorous stem cells divide symmetrically. Drosophila oogenesis Germline stem cells Spectrosome Centrosome separation Stem cell division Live imaging Agencia Estatal de...

... its presence in the ooplasm. Ooplasmic Jabba then prevents H2Av degradation, safeguarding the H2Av stockpile. Our findings provide insight into the mechanism for establishing histone stores during Drosophila oogenesis and shed light on the function of LDs as protein-sequestration sites. Author...

..., plays a major role in localizing Barrier-to-autointegration factor to the nuclear lamina, a partnership that contributes to stem cell maintenance. Nuclear lamina LEM-domain proteins Drosophila oogenesis Germline stem cells Barrier-to-autointegration factor Checkpoint kinase 2 Chk2...

...Katelynn M. Mannix; Rebecca M. Starble; Ronit S. Kaufman; Lynn Cooley ABSTRACT Gametogenesis is dependent on intercellular communication facilitated by stable intercellular bridges connecting developing germ cells. During Drosophila oogenesis, intercellular bridges (referred to as ring canals; RCs...

... by adipose Stunted ligand to brain Methuselah receptor . Science   353 , 1553 - 1556 . 10.1126/science.aaf8430 Drummond-Barbosa , D. and Spradling , A. C. ( 2001 ). Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis . Dev. Biol.   231 , 265 - 278...

... Summary: IMP regulates Notch signalling in follicle cells by controlling Kuzbanian localisation to the apical domain, where Notch cleavage occurs, revealing a novel regulatory step in the Notch pathway. RNA-binding protein Delta ADAM10 protease Drosophila oogenesis RNA-binding proteins...

...Andrew M. Hudson; Katelynn M. Mannix; Julianne A. Gerdes; Molly C. Kottemann; Lynn Cooley ABSTRACT During Drosophila oogenesis, specialized actin-based structures called ring canals form and expand to accommodate growth of the oocyte. Previous work demonstrated that Kelch and Cullin 3 function...

... contexts. Border cell (BC) migration during Drosophila oogenesis has emerged as an excellent genetic model for studying collective cell migration. BCs are of epithelial origin but acquire partial mesenchymal characteristics before migrating as a group towards the oocyte. Here, we report that insulin...

... signaling and antagonism between the Notch and JAK/STAT pathways . Development   134 , 1161 - 1169 . 10.1242/dev.02800 Bai , J. and Montell , D. ( 2002 ). Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis . Development   129 , 5377 - 5388 . 10.1242/dev.00115...

... by The Company of Biologists Ltd 2014 Clathrin heavy chain Drosophila oogenesis RNA localization Germ line Microtubules Polarity formation Studies in different organisms portray Bic-D homologs as factors that link the dynein-dynactin minus end-directed microtubule (MT) motor complex...

... The authors declare no competing financial interests. 19 6 2013 © 2013. Published by The Company of Biologists Ltd 2013 Chromatin insulator Drosophila oogenesis Neural gene expression Rbp9 Su(Hw) Transcriptional regulation Eukaryotic gene expression depends upon...

.... 18 4 2013 © 2013. Published by The Company of Biologists Ltd 2013 Traffic jam (Tj) Slow border cells (Slbo) DE-cadherin Jak/Stat Border cell migration Drosophila oogenesis Large Maf transcription factor Cell migration is indispensable for metazoan...

... for correspondence ( gavis@princeton.edu ) 28 10 2009 © 2010. 2010 Drosophila oogenesis bicoid Intracellular mRNA localization Swallow Staufen mRNA transport particles The asymmetric distribution of proteins within a cell is required to initiate and maintain cell polarity...

... polymerase II ). C T values used were the result of three different replicas from three independent experiments. Jak/Stat Germline stem cells Niche signalling BMP Drosophila oogenesis The generation, maintenance and repair of adult tissues and organs rely on populations of stem...

... localization. Thus, during Drosophila oogenesis, Rab6-dependent membrane trafficking is doubly required; first, for the general organization and growth of the egg chamber, and second, more specifically, for the polarization of the microtubule cytoskeleton and localization of oskar mRNA. These findings...

...Lisa N. Petrella; Tracy Smith-Leiker; Lynn Cooley An essential component of normal development is controlling the transition from cell proliferation to differentiation. One such transition occurs during Drosophila oogenesis. In early oogenesis, germ cells undergo mitotic proliferation and contain...

... characterize the Drosophila PRMT Capsuléen, homologous to human PRMT5. During Drosophila oogenesis, catalytic activity of Capsuléen is necessary for both the assembly of the nuage surrounding nurse cell nuclei and the formation of the pole plasm at the posterior end of the oocyte. In particular, we show...

.... Drosophila oogenesis epithelial migrations JNK signaling dual specificity phosphatase small GTPase © 2001 by Company of Biologists 2001 20 02 2001 19 04 2001 ‡ Present address: Centro de Biologio Molecular, Universidad Autonomo de Madrid, Madrid, Spain * Author...

...Jorge Bolívar; ean-René Huynh; Hernán López-Schier; Cayetano González; Daniel St Johnston; Acaimo González-Reyes ABSTRACT During early Drosophila oogenesis, one cell from a cyst of 16 germ cells is selected to become the oocyte, and accumulates oocyte-specific proteins and the centrosomes from...

... cells is due to overproliferation, we counted the number of cells using three-dimensional microscopy and found a twofold increase in the number of posterior follicle cells, but no changes in other follicle cells (data not shown). Drosophila oogenesis Merlin gurken bicoid oskar TGFα...