...Daisy J. Vinter; Caroline Hoppe; Thomas G. Minchington; Catherine Sutcliffe; Hilary L. Ashe ABSTRACT The Hunchback (Hb) transcription factor is crucial for anterior-posterior patterning of the Drosophila embryo. The maternal hb mRNA acts as a paradigm for translational regulation due to its...

... and beyond. We focus on a modern interpretation of this concept in terms of information theory, largely centered on its application to cell specification in the early Drosophila embryo. We argue that a true physical variable (position) is encoded in local concentrations of patterning molecules...

...Neta Rahimi; Inna Averbukh; Shari Carmon; Eyal D. Schejter; Naama Barkai; Ben-Zion Shilo ABSTRACT Establishment of morphogen gradients in the early Drosophila embryo is challenged by a diffusible extracellular milieu, and by rapid nuclear divisions that occur at the same time. To understand how...

... Summary: Robo2 is required in tendons to restrict Slit distribution by promoting its cleavage into a non-diffusible Slit-N, affecting muscle elongation towards tendons in Drosophila embryos. Drosophila embryo Muscle Robo Slit Slit cleavage In both vertebrates and invertebrates...

...-like apical contraction in cells after wounding the Drosophila pupal epidermis ( Antunes et al., 2013 ), and they may also help drive rapid wound repair in stage 7 Drosophila embryos ( Fernandez-Gonzalez and Zallen, 2013 ). The localisation of myosin flashes near to cell vertices suggests...

... Morphogenesis Drosophila embryo References Akam M. ( 1987 ). The molecular basis for metameric pattern in Drosophila embryo . Development 101 , 1 – 22 . Alexandre C. , Lecourtois M. , Vincent J. ( 1999 ). Wingless and Hedgehog pattern Drosophila denticle...

... Dorsal, a transcription factor that controls the dorsoventral pattern of the Drosophila embryo. ‡ Author for correspondence ( stas@princeton.edu ) * Present address: Department of Human Genetics, Cummings Life Science Center, University of Chicago, Chicago, IL 60637, USA Competing...

... from the interplay between Bicoid and Hunchback, which pattern the anteroposterior axis. *Author for correspondence (e-mail: mlevine@uclink4.berkeley.edu ) 30 4 2002 © 2002. 2002 Dorsoventral patterning Drosophila embryo Dorsal Pelle Twist Gradient thresholds...

...David N. Arnosti; Scott Barolo; Michael Levine; Stephen Small ABSTRACT Previous studies have provided a detailed model for the regulation of even-skipped ( eve ) stripe 2 expression in the Drosophila embryo. The bicoid (bcd) regulatory gradient triggers the expression of hunchback ( hb...

... 68 , 507 – 519 . Blochlinger , K. , Bodmer , R. , Jan , L. Y. and Jan , Y. N. ( 1990 ). Patterns of expression of Cut, a protein required for external sensory organ development in wild-Type and cut mutant Drosophila embryos . Genes Dev . 4 , 1322 – 1331...

...Saad Ibnsouda; François Schweisguth; Gérard de Billy; Alain Vincent ABSTRACT A dramatic reorganization of the cytoskeleton underlies the cellularisation of the syncytial Drosophila embryo. Formation of a regular network of acto-myosin filaments, providing a structural framework, and possibly...

...Takahiro Akiyama; Masukichi Okada ABSTRACT Mitochondria of early Drosophila embryos were observed with a transmission electron microscope and a fluorescent microscope after vital staining with rhodamine 123, which accumulates only in active mitochondria. Rhodamine 123 accumulated particularly...

..., in wild-type and cut mutant Drosophila embryos Genes Dev . 4 , 1322 – 1331 10.1101/gad.4.8.1322 Blochlinger , K. , Jan , L. Y. and Jan , Y. N. ( 1991 ) Transformation of sensory organ identity by ectopic expression of Cut in Drosophila Genes Dev 5 , 1124 – 1135...

... ( Letourneau, 1975 ; Bonhoeffer and Huf, 1982 ; Hammarback et al . 1988 ) and in vivo (Berlot and Goodman, 1983; Caudy and Bentley, 1986 ). In the Drosophila embryo, an adhesive substratum that permits RP3 axon extension may be confined to this region of musculature. Alternatively, a substance may...

... are withdrawn, generating the mature pattern of motor axon projections. There is no consistent, clear difference between the RP motorneurons in the relative timing of axon outgrowth. 27 02 1991 © 1991 by Company of Biologists 1991 Drosophila embryo motomeurons neural development axon...

...Carl Hashimoto; Suzanne Gerttula; Kathryn V. Anderson ABSTRACT Formation of the Drosophila embryo’s dorsal-ventral pattern requires the maternal product of the Toll gene. DNA sequence and genetic analyses together suggested that the Toll gene product is a transmembrane protein which communicates...

... and the surrounding cytoskeleton, that respond separately to the mitotic cues in the embryo and function together to give the synchronized early divisions. The Drosophila embryo has an ‘intermediate’ mitotic system in which the nuclear membrane does not break down completely during mitosis. We speculate...

...Ruth Lehmann; Hans Georg Frohnhöfer ABSTRACT The establishment of the segmental pattern in the Drosophila embryo is directed by three sets of maternal genes: the anterior, the terminal and the posterior group of genes. Embryos derived from females mutant for one of the posterior group genes lack...

... Drosophila embryo achaete-scute complex The structural and biochemical complexity of the nervous system is somehow coded for by the genome. How this is done, and how much genetic information is required to generate this complexity, is not known. Estimates of the number of unique mRNA sequences...

...A. Martinez Arias; N. E. Baker; P. W. Ingham Segment polarity genes are expressed and required in restricted domains within each metameric unit of the Drosophila embryo. We have used the expression of two segment polarity genes engrailed (en) and wingless (wg) to monitor the effects of segment...