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Keywords: Drosophila
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Journal Articles
Journal: Development
Development (2023) 150 (2): dev201563.
Published: 24 January 2023
... to activate MYC transcription. Psi, the sole FUBP protein in Drosophila , binds RNA to regulate P-element and mRNA splicing. Our previous work revealed pro-growth functions for Psi, which depend, in part, on transcriptional activation of Myc. Genome-wide functions for FUBP family proteins in transcriptional...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2023) 150 (2): dev201119.
Published: 18 January 2023
...Lenin Chandran; Wilko Backer; Raphael Schleutker; Deqing Kong; Seyed A. H. Beati; Stefan Luschnig; H.-Arno J. Müller ABSTRACT Src kinases are important regulators of cell adhesion. Here, we have explored the function of Src42A in junction remodelling during Drosophila gastrulation. Src42A...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (1): dev201248.
Published: 6 January 2023
...Kota Banzai; Takashi Nishimura ABSTRACT Evolutionarily conserved insulin/insulin-like growth factor (IGF) signaling (IIS) correlates nutrient levels to metabolism and growth, thereby playing crucial roles in development and adult fitness. In the fruit fly Drosophila , ImpL2, an ortholog of IGFBP7...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (23): dev200636.
Published: 13 December 2022
...Megan M. Corty; Alexandria L. Hulegaard; Jo Q. Hill; Amy E. Sheehan; Sue A. Aicher; Marc R. Freeman ABSTRACT Most invertebrate axons and small-caliber axons in mammalian peripheral nerves are unmyelinated but still ensheathed by glia. Here, we use Drosophila wrapping glia to study the development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (23): dev199842.
Published: 7 December 2022
.... This variety of responses relies on a conserved signaling pathway. Its logic includes a negative-feedback loop involving the Hh receptor Ptc. Here, using experiments and computational models we study and compare the different spatial signaling profiles downstream of Hh in several developing Drosophila organs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (22): dev200808.
Published: 18 November 2022
...Alix Goupil; Jan Peter Heinen; Riham Salame; Fabrizio Rossi; Jose Reina; Carole Pennetier; Anthony Simon; Patricia Skorski; Anxela Louzao; Allison J. Bardin; Renata Basto; Cayetano Gonzalez ABSTRACT While testing for genome instability in Drosophila as reported by unscheduled upregulation of UAS...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200940.
Published: 1 November 2022
...Peter H. Whitney; Bikhyat Shrestha; Jiahan Xiong; Tom Zhang; Christine A. Rushlow ABSTRACT Transcription in the early Drosophila blastoderm is coordinated by the collective action of hundreds of enhancers. Many genes are controlled by so-called ‘shadow enhancers’, which provide resilience...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200292.
Published: 31 October 2022
... enrichment and polarisation at parasegmental boundaries (PSBs) in early Drosophila embryos, from the start of germband extension at gastrulation and throughout the germband extended stages (stages 6 to 11). First, we find that Tartan is required during germband extension for actomyosin enrichment at PSBs...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (21): dev200440.
Published: 28 October 2022
...Yuya Ohhara; Naoki Yamanaka ABSTRACT Animals control their developmental schedule in accordance with internal states and external environments. In Drosophila larvae, it is well established that nutrient status is sensed by different internal organs, which in turn regulate production of insulin-like...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (19): dev200908.
Published: 7 October 2022
...Deanne Francis; Alondra S. Burguete; Amin S. Ghabrial ABSTRACT Larval terminal cells of the Drosophila tracheal system generate extensive branched tubes, requiring a huge increase in apical membrane. We discovered that terminal cells compromised for apical membrane expansion – mTOR-vATPase axis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (19): dev200701.
Published: 3 October 2022
... evolution, a variety of vesicles with individual functions arose, with some of them building up highly specialised subcellular compartments. In this study, we have analysed the biosynthesis of a new vesicular compartment present in the valve cells of Drosophila melanogaster . We show that the compartment...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (18): dev200286.
Published: 29 September 2022
...Holly N. Stephenson; Robert Streeck; Florian Grüblinger; Christian Goosmann; Alf Herzig ABSTRACT Proven roles for hemocytes (blood cells) have expanded beyond the control of infections in Drosophila . Despite this, the crucial role of hemocytes in post-embryonic development has long thought...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200495.
Published: 22 August 2022
... in Drosophila . Briefly, we show that a single illumination source is sufficient to stimulate mBeRFP and GFP simultaneously. We demonstrate that mBeRFP can be easily combined with classical green and red fluorescent proteins without any crosstalk. We also show that the low photobleaching of mBeRFP is suitable...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200190.
Published: 22 August 2022
... migration. CTPsyn was co-enriched with Actin at the leading edge of the Drosophila border cell cluster where PIP 2 was enriched, and this enrichment depended on the CTPsyn activity. Genetic interactions of border cell migration were found between CTPsyn mutant and genes in PI biosynthesis. The CTPsyn...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (15): dev200519.
Published: 11 August 2022
... at the cell surface. During Drosophila embryonic salivary gland (SG) invagination, the GPCR ligand Folded gastrulation (Fog) activates Rho1 signaling to drive apical constriction. The SG receptor that transduces the Fog signal into Rho1-dependent myosin activation has not been identified. Here, we reveal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (13): dev197442.
Published: 1 July 2022
...Gregory Logan; Wei-Chien Chou; Brooke M. McCartney ABSTRACT Cells reposition their nuclei for diverse specialized functions through a wide variety of cytoskeletal mechanisms. During Drosophila oogenesis, 15 nurse cells connected by ring canals to each other and the oocyte contract, ‘dumping...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (11): dev200153.
Published: 6 June 2022
... a previously unreported function for CtBP, showing that lowering CtBP dosage genetically suppresses Polycomb group (PcG) loss-of-function phenotypes while enhancing that of trithorax group (trxG) in Drosophila , suggesting that the role of CtBP in gene activation is more pronounced in fly development than...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200456.
Published: 16 May 2022
...Uwe Töpfer; Karla Yanín Guerra Santillán; Elisabeth Fischer-Friedrich; Christian Dahmann ABSTRACT The basement membrane is a specialized extracellular matrix (ECM) that is crucial for the development of epithelial tissues and organs. In Drosophila , the mechanical properties of the basement...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (7): dev199987.
Published: 31 March 2022
... brain size. One such gene is TRAIP , which has multiple functions in DDR. We characterized the Drosophila TRAIP homolog nopo , hereafter traip , and found that traip mutants ( traip − ) have a brain-specific defect in the mushroom body (MB). traip − MBs were smaller and contained fewer neurons...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (7): dev200217.
Published: 31 March 2022
.... Here, we show that the zinc-finger transcription factor Blimp-1 acts in secondary and tertiary pigment cells in the Drosophila retina to promote the formation of a bi-convex corneal lens with normal refractive power, and in cone cells to enable complete extension of the photoreceptor rhabdomeres. Blimp...
Includes: Supplementary data