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Keywords: Determination
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Journal Articles
Journal: Development
Development (2022) 149 (2): dev194407.
Published: 24 January 2022
... here that siRNA-mediated MITF silencing in 501mel and SK28 human melanoma cells leads to upregulation of FOXD3 ( Fig. 7 E-H). Fig. 7. MITF represses FOXD3 expression. (A-D) The relative amounts of FOXD3 and AXIN2 were determined by RT-qPCR from HEI-193 schwannoma and IPN 02.3 Schwann...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2021) 148 (8): dev198150.
Published: 16 April 2021
...? Integrating findings from diverse species, we conclude that the final commitment of the germline to gametogenesis – the process of germ cell determination – occurs after primordial germ cells (PGCs) colonize the gonads. Combining this understanding with medical findings, we present a model whereby germ cell...
Journal Articles
Journal: Development
Development (2013) 140 (2): 323–332.
Published: 15 January 2013
... identity. * Author for correspondence ( josh.gamse@vanderbilt.edu ) Competing interests statement The authors declare no competing financial interests. 5 11 2012 © 2013. Published by The Company of Biologists Ltd Specification Determination Differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4619–4630.
Published: 1 December 2006
... 2006 © 2006. 2006 Sox10 Neural crest Fate specification Determination Dorsal root ganglion Neurogenin Zebrafish Transgene Waardenburg-Shah syndrome In the trunk and tail, sensory neurons are clustered with support cells(glia) to form a reiterated segmental series...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (1): 211–220.
Published: 1 January 2002
...Daisuke Saito; Sayuri Yonei-Tamura; Kohko Kano; Hiroyuki Ide; Koji Tamura Limb-type-specific expression of Tbx5/Tbx4 plays a key role in drawing distinction between a forelimb and a hindlimb. Here, we show insights into specification and determination during commitment of limb-type identity...
Journal Articles
Journal: Development
Development (1991) 113 (Supplement_2): 1–8.
Published: 1 April 1991
... a description of the normal cell lineages. We are now exploiting the frog neural retina to perform the experimental manipulations needed to elucidate these strategies. Key words: fate, determination, fluorescent dextran, Xenopus, neural development. Introduction A fundamental issue of developmental biology con...
Journal Articles
Journal: Development
Development (1991) 113 (Supplement_2): 17–22.
Published: 1 April 1991
...Marianne Bronner-Fraser; Scott E. Fraser Neural crest cells migrate extensively and give rise to diverse cell types, including cells of the sensory and autonomic nervous systems. A major unanswered question concerning the neural crest is when and how the neural crest cells become determined...
Journal Articles
Journal: Development
Development (1986) 97 (Supplement): 31–44.
Published: 1 October 1986
... cellular (e.g. Sulston, Schierenberg, White & Thomson, 1983) and genetic (e.g. Sternberg & Horvitz, 1984) aspects of development have been studied extensively in C. elegans . Copyright © 1986 by Company of Biologists 1986 Caenorhabditis nematodes determination polarity prelocalization...
Journal Articles
Journal: Development
Development (1986) 97 (Supplement): 65–73.
Published: 1 October 1986
... single cells from this region and transplanting them into the blastocoel cavity of host embryos, we have shown that the determinative process that restricts blastomeres to this their normal fate occurs between the early blastula and early gastrula stages (Heasman et al. 1984). To progress towards...
Journal Articles
Journal: Development
Development (1985) 89 (Supplement): 297–316.
Published: 1 November 1985
... of presumptive primordia in the beginning gastrula is the expression of a real difference of these parts, whether they are already more or less predestined or ‘determined’ for their ultimate fate, or whether they are still indifferent and will not receive their determination until a later time.” Until recently...
Journal Articles
Journal: Development
Development (1985) 89 (Supplement): 333–347.
Published: 1 November 1985
... support the pathway of differentiation already in progress. Inductive interactions therefore refer to pluripotential systems which are open to a choice of potential Key words: inductive interaction, competence, determination, amphibia. 334 P. D. NIEUWKOOP pathways. It must be realised that an inductive...