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Keywords: De-differentiation
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Journal Articles
Journal: Development
Development (2011) 138 (16): 3367–3376.
Published: 15 August 2011
... by detaching from the hub. Following starvation-induced GSC loss, GSC numbers are restored by symmetric renewals. Furthermore, upon more severe (genetically induced) GSC loss, both symmetric renewal and de-differentiation (where interconnected spermatogonia fragment into pairs while moving towards...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (23): 5541–5550.
Published: 1 December 2002
... or inhibition of β-catenin degradation with LiCl or proteasome inhibitor caused de-differentiation of chondrocytes. Transcriptional activation ofβ-catenin by its nuclear translocation was sufficient to cause phenotypic loss of differentiated chondrocytes. Expression pattern of Jun, a known target gene of β...